Question · asked by 1 review

Summary of findings 2: PLD alone vs other conventional chemotherapy: Hand‐foot syndrome (grade ≥ 3)

It is very uncertain whether summary of findings 2: PLD alone changes hand‐foot syndrome (grade ≥ 3) compared with other conventional chemotherapy (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Summary of findings 2: PLD alone vs other conventional chemotherapy
Hand‐foot syndrome (grade ≥ 3) · adult women with recurrent platinum‐resistant EOC
It is very uncertain whether summary of findings 2: PLD alone changes hand‐foot syndrome (grade ≥ 3) compared with other conventional chemotherapy (very low certainty).
Pegylated liposomal doxorubicin for relapsed epithelial ovarian cancer (2023) · Cochrane Headline outcomes only
no estimate extracted6 studies · 2184 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pegylated liposomal doxorubicin for relapsed epithelial ovarian cancer
2023 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.