Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,520 questions · 1,575 findings · 175 reviews · Headline outcomes only

No studies found 239 · 15.2%GRADE not reported 59 · 3.7%Very low 337 · 21.4%Low 406 · 25.8%Moderate 410 · 26%High 124 · 7.9%

Tacrolimus 0.03% vs corticosteroids

Physician's assessment of global response of improvement, clear or excellent ‐ 6 weeks · people with atopic dermatitis

Tacrolimus 0.03% probably leads to higher physician's assessment of global response of improvement, clear or… compared with corticosteroids (moderate certainty).

4 findings from 1 review
Show 1 more finding

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

B3: Caesarean section – an all women · the woman

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in B3: Caesarean section – an all women compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

C1: Total deaths (after randomisation) up to early childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C1: Total deaths (after randomisation) up to early childhood compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

C2: Neurodevelopmental impairment at early childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C2: Neurodevelopmental impairment at early childhood compared with single course (high certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

C3: Survival free of neurodevelopmental impairment at early childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C3: Survival free of neurodevelopmental impairment at early childhood compared with single course (high certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

C4: Survival free of major neurodevelopmental impairment atearly childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C4: Survival free of major neurodevelopmental impairment atearly… compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

D1: Total deaths (after randomisation) up to mid‐ to later childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D1: Total deaths (after randomisation) up to mid‐ to later childhood compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

D2: Neurocognitive impairment atmid‐ to later childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D2: Neurocognitive impairment atmid‐ to later childhood compared with single course (low certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

D3: Survival free of neurocognitive impairment atmid‐ to later childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D3: Survival free of neurocognitive impairment atmid‐ to later… compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

D4: Survival free of major neurocognitive impairment atmid‐ to later childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D4: Survival free of major neurocognitive impairment atmid‐ to later… compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

Maternal death · the woman

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in B1: Maternal death – all women compared with single course (low certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

B2: Maternal sepsis – an all women · the woman

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in B2: Maternal sepsis – an all women compared with single course (moderate certainty).

1 finding from 1 review

Effects of different inhaled corticosteroids on growth in children with persistent asthma: fluticasone vs beclomethasone

Linear growth velocity (cm/year) · children up to 18 years of age with persistent asthma

Effects of different inhaled corticosteroids on growth in children… may leads to higher linear growth velocity (cm/year) compared with beclomethasone (low certainty).

1 finding from 1 review