Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,890 questions · 3,917 findings · 272 reviews · Oral Health

No studies found 429 · 11%GRADE not reported 2,657 · 67.8%Very low 512 · 13.1%Low 219 · 5.6%Moderate 80 · 2%High 20 · 0.5%

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Systolic blood pressure (mmHg), change from baseline · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… probably leads to lower change in systolic blood pressure (SBP, mmHg) compared with supra-gingival scaling (moderate certainty).

3 findings from 1 review

Poor / no tooth brushing habit vs Good tooth brushing habit

Dental caries · Individuals in East Africa assessed for dental caries

Poor tooth brushing was associated with significantly higher odds of dental caries (OR 1.967, 95% CI 1.205 to 3.211); certainty not graded.

1 finding from 1 review

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs placebo

Pain (dichotomous, present/absent on 6th-7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…

It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes presence of pain (dichotomous, yes/no on 6th-7th day) compared with placebo (very low certainty).

1 finding from 1 review

Frequent carbohydrate / sugary food intake vs Infrequent carbohydrate intake

Dental caries · Individuals in East Africa assessed for dental caries

Frequent carbohydrate intake was associated with significantly higher odds of dental caries (OR 1.575, 95% CI 1.13 to 3.051); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence · General population (children and adults) in East Africa

Caries prevalence in mixed dentition (6-12 years) was 41.3% (95% CI 33.5 to 49.2); certainty not graded.

1 finding from 1 review

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

Caregivers' preferences for oral hygiene care · Critically ill patients (adults and children) receiving mechanical ventilation in ICU

The review found no eligible studies for this question.

1 finding from 1 review

Toothbrushing (with or without antiseptics), as part of oral hygiene care vs No toothbrushing (with or without antiseptics)

Caregivers' preferences for oral hygiene care · Critically ill adults receiving mechanical ventilation in ICU

The review found no eligible studies for this question.

1 finding from 1 review

Resin-based fissure sealant (visible-light-polymerized) vs Fluoride varnish

Incidence of dentinal carious lesion on treated occlusal surfaces of molars or premolars (yes/no) · Children and adolescents (general population, aged under 20 years)

It is very uncertain whether resin-based fissure sealant (visible-light-polymerized) changes incidence of dentinal carious lesion on treated occlusal surfaces of… compared with fluoride varnish (very low certainty).

2 findings from 1 review

Air cleaning system (ACS) vs No air cleaning system

Reduction in level of contamination in aerosols (CFU) during cavity preparation · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether air cleaning system (ACS) changes reduction in level of contamination in aerosols (CFU) during cavity… compared with no air cleaning system (very low certainty).

1 finding from 1 review

Intervention not reported

Dental caries prevalence · Children (<12 years) and adolescents (12-18 years) with type 1 diabetes

Caries prevalence was highest in South American studies at 84% (95% CI 0.67 to 0.94); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence · Children (<12 years) and adolescents (12-18 years) with type 1 diabetes

Caries prevalence in Asian studies was 67% (95% CI 0.43 to 0.85); certainty not graded.

1 finding from 1 review