Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,550 questions · 1,617 findings · 161 reviews · Neonatal

No studies found 238 · 14.7%GRADE not reported 76 · 4.7%Very low 377 · 23.3%Low 567 · 35.1%Moderate 285 · 17.6%High 74 · 4.6%

High MCT formula vs low MCT formula

Weight gain · promoting short‐term growth of preterm infants
2 findings from 1 review

Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)

Full breastfeeding compared with not breastfeeding or partial breastfeeding · preterm infants

Breastfeeding with supplemental feeds by other than bottle may leads to higher full breastfeeding compared with not breastfeeding or partial… compared with breastfeeding with supplemental feeds by bottle (all trials) (low certainty).

1 finding from 1 review

Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)

Any breastfeeding (full and partial combined) compared with not breastfeeding · preterm infants

Breastfeeding with supplemental feeds by other than bottle probably leads to higher any breastfeeding (full and partial combined) compared with not… compared with breastfeeding with supplemental feeds by bottle (all trials) (moderate certainty).

1 finding from 1 review

Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)

Episodes of infection · preterm infants

Breastfeeding with supplemental feeds by other than bottle showed no clear difference in episodes of infection per infant compared with breastfeeding with supplemental feeds by bottle (all trials) (low certainty).

1 finding from 1 review

Surfactant administration via thin catheter (S‐TC) vs surfactant administration through an endotracheal tube (S‐ETT)

Death or bronchopulmonary dysplasia at 36 weeks PMA · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via thin catheter (S‐TC) probably leads to lower death or bronchopulmonary dysplasia (BPD) at 36 weeks' postmenstrual… compared with surfactant administration through an endotracheal tube (S‐ETT) (moderate certainty).

1 finding from 1 review