Findings

What do systematic reviews say?

1,247 questions · 1,321 findings · 334 reviews

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No studies found 73 · 5.5%GRADE not reported 31 · 2.3%Very low 500 · 37.9%Low 406 · 30.7%Moderate 247 · 18.7%High 64 · 4.8%

Geriatrician‐led inpatient management vs orthopaedic‐led inpatient management

Cognitive function · adults with dementia following hip fracture surgery

1 finding from 1 review

Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 87 participants
Very low

Pharmacological agents vs placebo or any other pharmacological agent

Pain VAS. Scale from: 0 to 10; higher score = more pain · patients with Buerger's disease

1 finding from 1 review

Pharmacological treatment for Buerger's disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

Personal protective equipment (PPE) types: more protective vs less protective

Usability score Range 1 to 5, higher indicating better · healthcare worker volunteers

1 finding from 1 review

Personal protective equipment for preventing highly infectious diseases due to exposure to contaminated body fluids in… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Very low

'As needed' administration (e.g. based on pain scales) vs monthly injections

Change in BCVA at 1 year (ETDRS letters score, the higher the score the better) · people with neovascular age‐related macular degeneration

1 finding from 1 review

Treatment regimens for administration of anti‐vascular endothelial growth factor agents for neovascular age‐related… 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 2299 participants
Moderate

'As needed' administration (e.g. based on pain scales) vs monthly injections

QoL · people with neovascular age‐related macular degeneration

1 finding from 1 review

Treatment regimens for administration of anti‐vascular endothelial growth factor agents for neovascular age‐related… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 498 participants
Low

Extended‐fixed vs monthly injections

Change in BCVA at 1 year (ETDRS letters score, the higher the score the better) · people with neovascular age‐related macular degeneration

1 finding from 1 review

Treatment regimens for administration of anti‐vascular endothelial growth factor agents for neovascular age‐related… 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1439 participants
Moderate

Resilience interventions vs control condition

Resilience Measured by: investigators measured resilience using different instruments; higher scores mean higher resilience Timing of outcome assessment: post‐intervention · healthcare workers

1 finding from 1 review

Psychological interventions to foster resilience in healthcare professionals 2020 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 690 participants
Very low

Resilience interventions vs control condition

Quality of life/Mental health outcome · healthcare workers

1 finding from 1 review

Psychological interventions to foster resilience in healthcare professionals 2020 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 1494 participants
Very low

Implementation interventions vs no intervention

HRQoL at 6 or 12 months · healthcare professionals providing stroke rehabilitation

Implementation interventions showed no clear difference in patient health status: HRQoL (EQ‐5D: –0.59 to 1, higher score… compared with no intervention (moderate certainty).

1 finding from 1 review

Implementation interventions to promote the uptake of evidence‐based practices in stroke rehabilitation 2020 · Cochrane Headline outcomes only
MD 0.01
2 studies · 1242 participants
Moderate

Implementation interventions vs no intervention

Patient health status: ADL (Barthel Index, 0–20, higher score = better) at up to 6 months · healthcare professionals providing stroke rehabilitation

Implementation interventions showed no clear difference in patient health status: ADL (Barthel Index, 0–20, higher score =… compared with no intervention (moderate certainty).

1 finding from 1 review

Implementation interventions to promote the uptake of evidence‐based practices in stroke rehabilitation 2020 · Cochrane Headline outcomes only
MD 0.29
2 studies · 1272 participants
Moderate

Implementation interventions vs no intervention

Patient health status: psychological well‐being (GHQ‐12, 0–36, higher score = worse) at up to 6 months · healthcare professionals providing stroke rehabilitation

Implementation interventions showed no clear difference in patient health status: psychological well‐being (GHQ‐12, 0–36,… compared with no intervention (low certainty).

1 finding from 1 review

Implementation interventions to promote the uptake of evidence‐based practices in stroke rehabilitation 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1273 participants
Low

Benzodiazepines (lorazepam) vs haloperidol

Severity of delirium · adult AIDS patients with delirium

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Very low

Benzodiazepines (lorazepam) vs haloperidol

Any adverse event ESRS, higher = worse · adult AIDS patients with delirium

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Very low

Benzodiazepines (lorazepam) vs chlorpromazine

Any adverse event ESRS, higher = worse · adult AIDS patients with delirium

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 19 participants
Very low

Wavefront‐optimized procedures vs wavefront‐guided procedures

Mean higher‐order aberrations (HOAs) post‐treatment, measured by machine with wavefront sensor ‐ 12 months · Adults with refractive errors

1 finding from 1 review

Wavefront excimer laser refractive surgery for adults with refractive errors 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 622 participants
Low

Wavefront‐guided LASIK vs wavefront‐guided PRK

Mean higher‐order aberrations (HOAs) post‐treatment, measured by machine with wavefront sensor ‐ 12 months · Adults with refractive errors

1 finding from 1 review

Wavefront excimer laser refractive surgery for adults with refractive errors 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 66 participants
Very low

Wavefront procedures vs conventional procedures

Proportion of eyes that had lost 1 or more lines of best spectacle‐corrected visual acuity (BSCVA) posttreatment‐procedure LASIK; Mean higher‐order aberrations (HOAs) post‐treatment, measured by machine with wavefront sensor; proportion of eyes wi... · Adults with refractive errors

The review found no eligible studies for this question.

1 finding from 1 review

Wavefront excimer laser refractive surgery for adults with refractive errors 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Hospital‐based specialist palliative care vs usual care

Health‐related quality of life (HRQoL) · adults with advanced illness and their unpaid caregivers/families

1 finding from 1 review

The effectiveness and cost‐effectiveness of hospital‐based specialist palliative care for adults with advanced illness… 2020 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1344 participants
Low

Hospital‐based specialist palliative care vs usual care

Patient satisfaction with careiii, SD units(higher scores indicate better patient satisfaction) · adults with advanced illness and their unpaid caregivers/families

1 finding from 1 review

The effectiveness and cost‐effectiveness of hospital‐based specialist palliative care for adults with advanced illness… 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 337 participants
Low

Intervention not reported

Patient harms associated with patient and family involvement in escalation of care (5a) Multiple Affect Adjective Checklist total score for state anxiety (range 0‐21). Higher scores signify higher anxiety; a score of ≥ 11 indicates clinically sign... · Adults (and/or family members) with potential for acute life‐threatening illness

1 finding from 1 review

Interventions to increase patient and family involvement in escalation of care for acute life‐threatening illness in… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 2597 participants
Moderate