Vomiting, diarrhoea or rash · children with acute otitis media
Immediate antibiotics leads to higher vomiting, diarrhoea or rash compared with expectant observation (high certainty).
1 finding from 1 review
Abnormal tympanometry ‐ 1 month · children with acute otitis media
Immediate antibiotics showed no clear difference in abnormal tympanometry at 4 weeks compared with expectant observation (moderate certainty).
1 finding from 1 review
Pain ‐ pain at 2 to 3 days · children with acute otitis media
Immediate antibiotics may leads to lower pain ‐ Pain at 2 to 3 days compared with expectant observation (low certainty).
1 finding from 1 review
Pain ‐ Pain at 3 to 7 days · children with acute otitis media
Immediate antibiotics showed no clear difference in pain ‐ Pain at 3 to 7 days compared with expectant observation (moderate certainty).
1 finding from 1 review
Wound infection · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) compared with placebo (very low certainty).
2 findings from 1 review
DSSI · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
Antibiotic prophylaxis showed no clear difference in DSSI compared with placebo (moderate certainty).
1 finding from 1 review
DSSI ‐ low infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
Antibiotic prophylaxis showed no clear difference in DSSI ‐ low infection risk environment compared with placebo (moderate certainty).
1 finding from 1 review
DSSI ‐ high infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
Antibiotic prophylaxis showed no clear difference in DSSI ‐ high infection risk environment compared with placebo (low certainty).
1 finding from 1 review
All wound infections (SSSI + DSSI) ‐ low infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) ‐ low infection risk environment compared with placebo (very low certainty).
2 findings from 1 review
All wound infections (SSSI + DSSI) ‐ high infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) ‐ high infection risk environment compared with placebo (very low certainty).
2 findings from 1 review
SSSI · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
Antibiotic prophylaxis probably leads to lower SSSI compared with placebo (moderate certainty).
1 finding from 1 review
SSSI ‐ low infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
Antibiotic prophylaxis showed no clear difference in SSSI ‐ low infection risk environment compared with placebo (moderate certainty).
1 finding from 1 review
SSSI ‐ high infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair
It is very uncertain whether antibiotic prophylaxis changes SSSI ‐ high infection risk environment compared with placebo (very low certainty).
1 finding from 1 review
Incidence of episiotomy wound infection with wound dehiscence · women with episiotomy repair following vaginal birth
It is very uncertain whether antibiotic prophylaxis changes incidence of episiotomy wound infection with wound dehiscence compared with no treatment (very low certainty).
1 finding from 1 review
RR 0.13 [0.01, 2.28]
73 participants
Very low
Incidence of episiotomy wound dehiscence without wound infection · women with episiotomy repair following vaginal birth
It is very uncertain whether antibiotic prophylaxis changes incidence of episiotomy wound dehiscence without wound infection compared with no treatment (very low certainty).
1 finding from 1 review
RR 0.82 [0.29, 2.34]
73 participants
Very low
Incidence of puerperal infection (endometritis) · women with episiotomy repair following vaginal birth
1 finding from 1 review
no estimate extracted
73 participants
Very low
Incidence of severe maternal infectious morbidity · women with episiotomy repair following vaginal birth
1 finding from 1 review
Discomfort or pain at episiotomy wound site · women with episiotomy repair following vaginal birth
1 finding from 1 review
Women's satisfaction with care · women with episiotomy repair following vaginal birth
1 finding from 1 review
Infection rate at 2 weeks postpartum ‐ perineal wound infection in third‐ or fourth‐degree tear · Women with third‐ and fourth‐degree perineal tear during vaginal birth
Antibiotic prophylaxis probably leads to lower infection rate at 2 weeks postpartum ‐ perineal wound infection in… compared with no treatment (moderate certainty).
1 finding from 1 review