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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,645 questions in 107 reviews · Wounds

current versions
No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Basic wound contact dressing vs polyurethane matrix hydrocolloid dressings
Ease of dressing removal Assessment method: asked whether dressings were difficult to remove (yes) · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
RR 12.61 study · 173 participantsVery low
Basic wound contact dressing vs silver dressing
SSI potentially contaminated surgery SSI Assessment method: various clinical measures · surgical wounds resulting from a range of surgical procedures with some risk of contamination healing by primary…
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs exposed wound
Acceptability of dressing to participant Clean surgery Assessment method: VAS · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs silver dressing
Scarring · surgical wounds resulting from a range of surgical procedures with some risk of contamination healing by primary…
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs silver dressing
Acceptability of dressing to participant · surgical wounds resulting from a range of surgical procedures with some risk of contamination healing by primary…
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs silver dressing
Ease of dressing removal · surgical wounds resulting from a range of surgical procedures with some risk of contamination healing by primary…
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs non‐silver antimicrobial dressings
SSI Assessment method: CDC definition of SSI · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs non‐silver antimicrobial dressings
Scarring · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs non‐silver antimicrobial dressings
Acceptability of dressing to participant · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs non‐silver antimicrobial dressings
Ease of dressing removal · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs exposed wound
Ease of dressing removal · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Film dressing vs exposed wound
SSI Assessment method: undefined method · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
RR 0.2 [0.02, 1.69]1 study · 107 participantsVery low
Film dressing vs exposed wound
Scarring (further information not reported) · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extracted1 study · 107 participantsVery low
Film dressing vs exposed wound
Acceptability of dressing to participant · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extracted1 study · 107 participantsVery low
Film dressing vs exposed wound
Ease of dressing removal · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Silver dressing vs exposed wound
SSI Assessment method: CDC definition of SSI · surgical wounds resulting from surgery at risk of contamination and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
RR 8 [1.02, 62.55]1 study · 166 participantsVery low
Autologous platelet‐rich plasma vs standard care with/without placebo
Chronic wounds (all) completely healed · adults with chronic wounds
Autologous platelet‐rich plasma for treating chronic wounds (2016) · Cochrane
RR 1.19 [0.95, 1.5]8 studies · 391 participantsLow
Autologous platelet‐rich plasma vs standard care with/without placebo
Chronic wounds (diabetic foot ulcers) completely healed · adults with chronic wounds
Autologous platelet‐rich plasma for treating chronic wounds (2016) · Cochrane
RR 1.22 [1.01, 1.49]2 studies · 189 participantsLow
Autologous platelet‐rich plasma vs standard care with/without placebo
Chronic wounds (venous leg ulcers) completely healed · adults with chronic wounds
Autologous platelet‐rich plasma for treating chronic wounds (2016) · Cochrane
RR 1.02 [0.81, 1.27]2 studies · 101 participantsLow
Autologous platelet‐rich plasma vs standard care with/without placebo
Adverse events · adults with chronic wounds
Autologous platelet‐rich plasma for treating chronic wounds (2016) · Cochrane
RR 1.05 [0.29, 3.88]3 studies · 102 participantsVery low
Leg Club vs nurse home visits
Number of people healed · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
RR 1.55 [0.81, 2.93]1 study · 67 participantsLow
Lively Legs programme vs wounds outpatient clinic
Adverse events ‐ not reported · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extractedNRNo studies
Lively Legs programme vs wounds outpatient clinic
Recurrence of ulcers · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
RR 0.82 [0.59, 1.14]1 study · 136 participantsLow
Lively Legs programme vs wounds outpatient clinic
Quality of life ‐ not reported · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extractedNRNo studies
Lively Legs programme vs wounds outpatient clinic
Adherence to compression · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
RR 1.02 [0.74, 1.41]1 study · 184 participantsLow
Lively Legs programme vs wounds outpatient clinic
Pain ‐ not measured · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extractedNRNo studies
Video education vs written education
Number of people healed ‐ not reported · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extractedNRNo studies
Video education vs written education
Proportion with recurrence ‐ not reported · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extractedNRNo studies
Video education vs written education
Adherence to compression ‐ not reported · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extractedNRNo studies
Video education vs written education
Quality of life ‐ not reported · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extractedNRNo studies
Video education vs written education
Pain at 6 months ‐ not reported · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extractedNRNo studies
Leg Club vs nurse home visits
Recurrence of ulcers ‐ not reported · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extractedNRNo studies
Video education vs written education
Adverse events ‐ not reported · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extractedNRNo studies
Leg Club vs nurse home visits
Time to healing ‐ not reported · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extractedNRNo studies
Leg Club vs nurse home visits
Adverse events ‐ not reported · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extractedNRNo studies
Leg Club vs nurse home visits
Quality of life Spitzer's quality of life index. Scale from 0‐10. · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extracted1 study · 52 participantsLow
Leg Club vs nurse home visits
Adherence to compression ‐ not reported · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extractedNRNo studies
Leg Club vs nurse home visits
Pain Medical Outcomes Study Pain Measures. Scale from: 0 to 100. · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extracted1 study · 60 participantsLow
Lively Legs programme vs wounds outpatient clinic
Time to healing ‐ not reported · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
no estimate extractedNRNo studies
Lively Legs programme vs wounds outpatient clinic
Number of people healed · people with venous leg ulcers
Interventions for helping people adhere to compression treatments for venous leg ulceration (2016) · Cochrane
RR 1.24 [0.93, 1.67]1 study · 184 participantsLow
Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes
Catheter‐related blood stream infection (CRBSI) · patients with a central venous access device
Frequency of dressing changes for central venous access devices on catheter‐related infections (2016) · Cochrane
RR 1.42 [0.4, 4.98]NRLow
Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes
All‐cause mortality · patients with a central venous access device
Frequency of dressing changes for central venous access devices on catheter‐related infections (2016) · Cochrane
RR 1.06 [0.9, 1.25]NRLow
Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes
Skin damage № of participants: 1587 (4 RCTs) · patients with a central venous access device
Frequency of dressing changes for central venous access devices on catheter‐related infections (2016) · Cochrane
no estimate extractedNRVery low
Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes
Pain № of participants: 193 (2 RCTs) · patients with a central venous access device
Frequency of dressing changes for central venous access devices on catheter‐related infections (2016) · Cochrane
RR 0.8 [0.46, 1.38]NRLow
Intervention NR
Average time for ulcer healing · patients with venous leg ulcers
Oral aspirin for treating venous leg ulcers (2016) · Cochrane
no estimate extracted1 study · 51 participantsLow
Intervention NR
Reduction of ulcer area (median) · patients with venous leg ulcers
Oral aspirin for treating venous leg ulcers (2016) · Cochrane
no estimate extracted1 study · 20 participantsLow
Intervention NR
Proportion of healed ulcers in the trial period · patients with venous leg ulcers
Oral aspirin for treating venous leg ulcers (2016) · Cochrane
no estimate extracted1 study · 20 participantsLow
Intervention NR
Major bleeding · patients with venous leg ulcers
Oral aspirin for treating venous leg ulcers (2016) · Cochrane
no estimate extracted1 study · 20 participantsLow
Intervention NR
Average time of ulcer recurrence · patients with venous leg ulcers
Oral aspirin for treating venous leg ulcers (2016) · Cochrane
no estimate extracted1 study · 51 participantsLow
Intervention NR
Mortality · patients with venous leg ulcers
Oral aspirin for treating venous leg ulcers (2016) · Cochrane
no estimate extractedNRNo studies