Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,245 questions · 1,274 findings · 321 reviews

No studies found 247 · 19.4%GRADE not reported 195 · 15.3%Very low 372 · 29.2%Low 282 · 22.1%Moderate 141 · 11.1%High 37 · 2.9%

Summary of findings: Trihexyphenidyl vs placebo

Participation in activities of daily living:individual goal setting Measured by: GAS (up to 5 functional goals scored on a 5‐point scale (−2 = much less than expected to +2 = much more than expected); higher score = better than expected outcome) · children with dystonic cerebral palsy
1 finding from 1 review

Summary of findings. Surgery (percutaneous wire fixation) vs not surgery (cast only)

'Treatment failure': various secondary procedures such as remanipulation for early loss of position; early or more complex wire removal ( · children with displaced distal radius fracture with intact or involved or displaced ulna fracture (both‐bone fracture)

It is very uncertain whether summary of findings. Surgery (percutaneous wire fixation) changes 'Treatment failure': various secondary procedures such as… compared with not surgery (cast only) (very low certainty).

1 finding from 1 review

Summary of findings. Surgery (percutaneous wire fixation) vs not surgery (cast only)

Serious adverse events (typically more serious complications) ( · children with displaced distal radius fracture with intact or involved or displaced ulna fracture (both‐bone fracture)

It is very uncertain whether summary of findings. Surgery (percutaneous wire fixation) changes serious adverse events (typically more serious complications) ( compared with not surgery (cast only) (very low certainty).

1 finding from 1 review