Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,720 questions · 15,377 findings · 900 reviews

No studies found 3,865 · 25.1%GRADE not reported 2,291 · 14.9%Very low 3,875 · 25.2%Low 3,287 · 21.4%Moderate 1,681 · 10.9%High 378 · 2.5%

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Summary of findings table ‐ Indicated prevention interventions vs control group

Diagnosis of mental disorders at study endpoint (RR < 1 denotes lower risk of mental diagnosis) · preventing mental disorders

It is very uncertain whether summary of findings table ‐ Indicated prevention interventions changes diagnosis of mental disorders at study endpoint (RR < 1 denotes… compared with control group (very low certainty).

2 findings from 1 review

Summary of findings table ‐ Indicated prevention interventions vs control group

QoL · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Indicated prevention interventions vs control group

Adverse events at study endpoint · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Indicated prevention interventions vs control group

Psychological functioning and impairment at study endpoint (higher score = higher disability) · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Indicated prevention interventions vs control group

Depressive symptoms · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Indicated prevention interventions vs control group

Anxiety · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Indicated prevention interventions vs control group

Distress/PTSD symptoms at study endpoint (higher score = higher severity) · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Selective prevention interventions vs control group

Diagnosis of mental disorders at study endpoint · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Selective prevention interventions vs control group

QoL · preventing mental disorders
2 findings from 1 review

Primary health professional‐led or collaborative care vs usual or enhanced care

Depressive symptoms · women with perinatal depression

It is very uncertain whether primary health professional‐led collaborative care interventions changes depression symptoms ‐ intermediate term (1 to 6 months post… compared with usual or enhanced care (very low certainty).

1 finding from 1 review

Primary health professional‐led or collaborative care vs usual or enhanced care

Quality of life ‐ intermediate term (1 to 6 months post intervention) SF‐36 social functioning (higher score = higher quality of life) · women with perinatal depression

It is very uncertain whether primary health professional‐led collaborative care interventions changes quality of life ‐ intermediate term (1 to 6 months post… compared with usual or enhanced care (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Incidence of depression ‐ short‐term: < 6 months · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes incidence of depression ‐ short‐term: < 6 months compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Incidence of depression ‐ medium term: 6‐12 months · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes incidence of depression ‐ medium‐term: 6‐12 months compared with placebo (very low certainty).

1 finding from 1 review