Stability: Little's Irregularity Index (lower arch) · People who had received fixed appliance orthodontic treatment
It is very uncertain whether full-time wear of removable retainer (any type) changes stability: Little's Irregularity Index (lower arch) compared with part-time wear of removable retainer (any type) (very low certainty).
1 finding from 1 review
Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer
1 finding from 1 review
Adverse events: significant difference in complication rates, lower for supraomohyoid (SOND 13.0% vs MRND 21.9%, P=0.040). UW-QOL at 1 year: supraomohyoid superior in pain relief (78.8% vs 75.2%, P=0.013) and shoulder…
1 study · 332 participants
Very low
Locoregional recurrence · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
PET-CT following chemoradiotherapy (neck dissection only if… showed no clear difference in locoregional recurrence compared with planned neck dissection before or after chemoradiotherapy (moderate certainty).
1 finding from 1 review
Locoregional recurrence · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
Elective neck dissection (at time of primary tumour resection) probably leads to lower locoregional recurrence compared with therapeutic (delayed) neck dissection (moderate certainty).
1 finding from 1 review
Adverse effects on oral health: gingival bleeding (lower arch) · People who had received fixed appliance orthodontic treatment
It is very uncertain whether full-time clear plastic (removable) retainer changes adverse effects on oral health: gingival bleeding (lower arch) compared with any type of fixed (bonded) retainer (very low certainty).
1 finding from 1 review
Total mortality · Adults with oral cavity or oropharyngeal cancer
1 finding from 1 review
Recurrence · Adults with oral cavity cancer
It is very uncertain whether elective radical (comprehensive) neck dissection changes recurrence compared with elective selective neck dissection (very low certainty).
1 finding from 1 review
Recurrence · Adults with oral cavity or oropharyngeal cancer
1 finding from 1 review
Stability: Little's Irregularity Index (lower arch) · People who had received fixed appliance orthodontic treatment
It is very uncertain whether full-time clear plastic (removable) retainer changes stability: Little's Irregularity Index (lower arch) compared with any type of fixed (bonded) retainer (very low certainty).
1 finding from 1 review
Mortality (overall survival) · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
Elective neck dissection (at time of primary tumour resection) probably leads to lower mortality (overall survival) compared with therapeutic (delayed) neck dissection (moderate certainty).
1 finding from 1 review
Disease-free survival · Adults with oral cavity or oropharyngeal cancer
Sentinel node biopsy (neck dissection only if biopsy positive) showed no clear difference in disease-free survival (new disease, progression, and mortality) compared with elective neck dissection (low certainty).
1 finding from 1 review
Locoregional recurrence · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
1 finding from 1 review
Locoregional recurrence: data not presented usably and inconsistent; Pandey 2018 no difference (3/12 vs 3/20); Rastogi 2018 lower recurrence with superselective (Kaplan-Meier P<0.05); 72 participants (2 RCTs).
2 studies · 72 participants
Very low
Disease-free survival · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
Elective neck dissection (at time of primary tumour resection) probably leads to lower disease-free survival (new disease, progression, and mortality) compared with therapeutic (delayed) neck dissection (moderate certainty).
1 finding from 1 review
Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer
1 finding from 1 review
Adverse events: severe acute effects in both groups (subcutaneous fibrosis, telangiectasia, moderate-to-severe oedema, xerostomia, trismus, dysphagia); subcutaneous fibrosis more prevalent with surgery + radiotherapy…
1 study · 35 participants
Very low
Adverse effects on oral health: Gingival Index (lower arch) · People who had received fixed appliance orthodontic treatment
The review found no eligible studies for this question.
1 finding from 1 review
Side effects or other adverse events · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
The review found no eligible studies for this question.
1 finding from 1 review
Locoregional recurrence · Adults with oral cavity or oropharyngeal cancer
1 finding from 1 review
Locoregional recurrence: reported difference between groups not statistically significant (P=0.355), but no useable data; 32 participants (1 RCT, Iyer 2015).
1 study · 32 participants
Very low
Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
1 finding from 1 review
Duration of orthodontic treatment: alignment stage (mandibular arch) · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
It is very uncertain whether light-emitting diode (LED) photobiomodulation changes duration of orthodontic treatment: alignment stage (mandibular arch) compared with conventional orthodontic appliance treatment (very low certainty).
1 finding from 1 review
Disease-free survival · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
1 finding from 1 review