Physical function · children with displaced distal radius fracture with intact or involved or displaced ulna fracture (both‐bone fracture)
The review found no eligible studies for this question.
2 findings from 1 review
'Treatment failure': various secondary procedures such as remanipulation for early loss of position; early or more complex wire removal ( · children with displaced distal radius fracture with intact or involved or displaced ulna fracture (both‐bone fracture)
It is very uncertain whether summary of findings. Surgery (percutaneous wire fixation) changes 'Treatment failure': various secondary procedures such as… compared with not surgery (cast only) (very low certainty).
1 finding from 1 review
Serious adverse events (typically more serious complications) ( · children with displaced distal radius fracture with intact or involved or displaced ulna fracture (both‐bone fracture)
It is very uncertain whether summary of findings. Surgery (percutaneous wire fixation) changes serious adverse events (typically more serious complications) ( compared with not surgery (cast only) (very low certainty).
1 finding from 1 review
Return to normal activities (days) · children with displaced distal radius fracture with intact or involved or displaced ulna fracture (both‐bone fracture)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Wrist pain · children with displaced distal radius fracture with intact or involved or displaced ulna fracture (both‐bone fracture)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Minor complications (less serious).j Here represented by referral for physical therapy for range of motion limitation (post‐immobilisation after 4 weeks) · children with displaced distal radius fracture with intact or involved or displaced ulna fracture (both‐bone fracture)
It is very uncertain whether summary of findings. Surgery (percutaneous wire fixation) changes minor complications (less serious).j Here represented by referral… compared with not surgery (cast only) (very low certainty).
1 finding from 1 review
Survival ‐ overall · Women (70 years plus) with operable primary breast cancer
Surgery plus endocrine therapy showed no clear difference in survival ‐ overall compared with primary endocrine therapy (low certainty).
1 finding from 1 review
Local tumor control · Women (70 years plus) with operable primary breast cancer
Surgery plus endocrine therapy leads to lower local disease control compared with primary endocrine therapy (high certainty).
1 finding from 1 review
Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
Hyperbaric oxygen therapy plus standard care (surgery, antibiotics,… showed no clear difference in healing of osteonecrosis - improvement ('healed' or 'improved' vs… compared with standard care alone (surgery, antibiotics, oral rinse); GRADE not reported.
5 findings from 1 review
RR 1.75 [0.51, 5.98]
1 study · 18 participants
GRADE not reported
RR 1.78 [0.97, 3.28]
1 study · 46 participants
GRADE not reported
RR 1.94 [1.01, 3.74]
1 study · 45 participants
Very low
Show 2 more findings
Healing of osteonecrosis - healed ('healed' vs 'improved', 'unchanged' or 'worse') · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
Hyperbaric oxygen therapy plus standard care (surgery, antibiotics,… showed no clear difference in healing of osteonecrosis - healed ('healed' vs 'improved',… compared with standard care alone (surgery, antibiotics, oral rinse); GRADE not reported.
5 findings from 1 review
RR 1.56 [0.77, 3.18]
1 study · 46 participants
GRADE not reported
RR 1.00 [0.25, 4.00]
1 study · 18 participants
GRADE not reported
RR 0.95 [0.44, 2.04]
1 study · 40 participants
GRADE not reported
Show 2 more findings
Pain · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
1 finding from 1 review
Adverse effects · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Quality of life · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
1 finding from 1 review
Overall survival, induction cisplatin + 5-fluorouracil + docetaxel prior to concurrent chemoradiation (cisplatin) vs concurrent chemoradiation (cisplatin) · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… showed no clear difference in overall survival, induction cisplatin + 5-fluorouracil + docetaxel… compared with locoregional treatment (radiotherapy and/or surgery) alone (low certainty).
1 finding from 1 review
Locoregional control · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… led to lower locoregional control, induction cisplatin + 5-fluorouracil +… compared with locoregional treatment (radiotherapy and/or surgery) alone; GRADE not reported.
1 finding from 1 review
RR 0.80 [0.64, 0.99]
3 studies
GRADE not reported
Overall survival, induction platinum + 5-fluorouracil prior to radiotherapy vs radiotherapy alone · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… showed no clear difference in overall survival, induction platinum + 5-fluorouracil prior to… compared with locoregional treatment (radiotherapy and/or surgery) alone (moderate certainty).
1 finding from 1 review
Disease-free survival · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… led to lower disease-free survival, induction platinum + 5-fluorouracil prior to… compared with locoregional treatment (radiotherapy and/or surgery) alone; GRADE not reported.
1 finding from 1 review
Overall survival, induction cisplatin + 5-fluorouracil prior to concurrent chemoradiation (cisplatin) vs concurrent chemoradiation (cisplatin) · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… showed no clear difference in overall survival, induction cisplatin + 5-fluorouracil prior to… compared with locoregional treatment (radiotherapy and/or surgery) alone (low certainty).
1 finding from 1 review
Overall survival at 2 years · people with metastatic breast cancer
It is very uncertain whether breast surgery plus systemic treatment changes overall survival at 2 years compared with systemic treatment (very low certainty).
1 finding from 1 review
Quality of life · people with metastatic breast cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found