Question · asked by 1 review

Breast surgery plus systemic treatment vs systemic treatment: Overall survival at 2 years

It is very uncertain whether breast surgery plus systemic treatment changes overall survival at 2 years compared with systemic treatment (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Breast surgery plus systemic treatment vs systemic treatment
Overall survival at 2 years · metastatic breast cancer
It is very uncertain whether breast surgery plus systemic treatment changes overall survival at 2 years compared with systemic treatment (very low certainty).
Breast surgery for metastatic breast cancer (2018) · Cochrane Headline outcomes only
HR 0.83 [0.53, 1.31]2 studies · 624 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Breast surgery for metastatic breast cancer
2018 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.