Cochrane · systematic review · CD004272
Surgery versus primary endocrine therapy for operable primary breast cancer in elderly women (70 years plus)
Morgan, J, Wyld, L, Collins, KA, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Breast CancerAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 66.7%Moderate 0 · 0%High 1 · 33.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Surgery compared to primary endocrine therapy for operable primary breast cancer in elderly women (70 years plus)
Population: Women (70 years plus )with operable primary breast cancer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Survival ‐ overall Surgery vs primary endocrine therapy | HR 0.98 [0.81, 1.2] | 3 studies · 495 participants | Low |
Surgery plus endocrine therapy compared to primary endocrine therapy for operable primary breast cancer in elderly women (70 years plus)
Population: Women (70 years plus) with operable primary breast cancer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Survival ‐ overall Surgery plus endocrine therapy vs primary endocrine therapy | HR 0.86 [0.73, 1] | 3 studies · 1076 participants | Low |
Local disease control Surgery plus endocrine therapy vs primary endocrine therapy | HR 0.28 [0.23, 0.35] | 2 studies · 929 participants | High |