What do systematic reviews say?

Alternative desks and workstations vs sit‐desks

• Workplace interventions for reducing sitting at work 2018 · Cochrane Headline outcomes only
  no estimate extracted
  74 participants
  Very low
• Workplace interventions for reducing sitting at work 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Workplace policy changes vs alternate intervention or no intervention

The review found no eligible studies for this question.

• Workplace interventions for reducing sitting at work 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: intravitreal bevacizumab plus intravitreal steroid vs intravitreal steroid

The review found no eligible studies for this question.

• Anti‐vascular endothelial growth factor combined with intravitreal steroids for diabetic macular oedema 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: intravitreal bevacizumab plus intravitreal steroid vs macular laser

The review found no eligible studies for this question.

• Anti‐vascular endothelial growth factor combined with intravitreal steroids for diabetic macular oedema 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Metabolomics vs non metabolomics

Metabolomics showed no clear difference in multiple pregnancy (presence of more than 1 gestational sac) compared with non metabolomics (low certainty).

• Metabolomics for improving pregnancy outcomes in women undergoing assisted reproductive technologies 2018 · Cochrane Headline outcomes only
  OR 1.5 [0.7, 3.19]
  2 studies · 180 participants
  Low

Blue‐light filtering intraocular lenses (IOL) vs non blue‐light filtering IOL

• Blue‐light filtering intraocular lenses (IOLs) for protecting macular health 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 63 participants
  Very low

Descemet’s membrane endothelial keratoplasty (DMEK) vs Descemet’s stripping automated endothelial keratoplasty (DSAEK)

• Descemet's membrane endothelial keratoplasty (DMEK) versus Descemet's stripping automated endothelial keratoplasty… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Multifactorial interventions vs exercise

It is very uncertain whether multifactorial interventions changes number of people sustaining one or more falls compared with exercise (very low certainty).

• Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
  RR 0.26 [0.01, 5.52]
  1 study · 51 participants
  Very low

Multifactorial interventions vs exercise

The review found no eligible studies for this question.

• Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Multifactorial interventions vs exercise

The review found no eligible studies for this question.

• Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Multi‐component intervention vs usual care or attention control

Multiple component interventions probably leads to lower number of people sustaining one or more falls compared with usual care or attention control (moderate certainty).

• Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
  RR 0.82 [0.74, 0.9]
  11 studies · 1980 participants
  Moderate

Multi‐component intervention vs usual care or attention control

Multiple component interventions showed no clear difference in number of people sustaining recurrent falls (defined as two or more… compared with usual care or attention control (low certainty).

• Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
  RR 0.81 [0.63, 1.05]
  4 studies · 662 participants
  Low

Multifactorial interventions vs usual care or attention control

Multifactorial interventions showed no clear difference in number of people sustaining one or more falls compared with usual care or attention control (low certainty).

• Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
  RR 0.96 [0.9, 1.03]
  29 studies · 9637 participants
  Low

Multi‐component intervention vs usual care or attention control

It is very uncertain whether multiple component interventions changes number of people sustaining one or more fall‐related fractures compared with usual care or attention control (very low certainty).

• Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
  RR 0.5 [0.05, 5.32]
  2 studies · 232 participants
  Very low

Multi‐component intervention vs exercise

Multiple component interventions showed no clear difference in number of people sustaining one or more falls compared with exercise (low certainty).

• Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
  RR 0.93 [0.78, 1.1]
  3 studies · 863 participants
  Low

Multi‐component intervention vs exercise

The review found no eligible studies for this question.

• Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Multi‐component intervention vs exercise

The review found no eligible studies for this question.

• Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Multifactorial interventions vs usual care or attention control

Multifactorial interventions showed no clear difference in number of people sustaining recurrent falls (defined as 2 or more… compared with usual care or attention control (low certainty).

• Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
  RR 0.87 [0.74, 1.03]
  12 studies · 3368 participants
  Low

Multifactorial interventions vs usual care or attention control

Multifactorial interventions showed no clear difference in number of people sustaining one or more fall‐related fractures compared with usual care or attention control (low certainty).

• Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
  RR 0.73 [0.53, 1.01]
  9 studies · 2850 participants
  Low

Nd:YAG laser vs argon‐green laser

It is very uncertain whether nd:YAG laser changes BCVA: loss of 15 or more ETDRS letters compared with argon‐green laser (very low certainty).

• Different lasers and techniques for proliferative diabetic retinopathy 2018 · Cochrane Headline outcomes only
  RR 0.8 [0.3, 2.13]
  1 study · 20 participants
  Very low