Cochrane · systematic review · CD012097
Descemet's membrane endothelial keratoplasty (DMEK) versus Descemet's stripping automated endothelial keratoplasty (DSAEK) for corneal endothelial failure
Stuart, AJ, Romano, V, Virgili, G, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 4 · 66.7%Low 2 · 33.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Descemet’s membrane endothelial keratoplasty (DMEK) compared with Descemet’s stripping automated endothelial keratoplasty (DSAEK) for corneal endothelial failure
Population: participants/eyes with corneal endothelial failure
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
BCVA logMAR, 12 months' Descemet’s membrane endothelial keratoplasty (DMEK) vs Descemet’s stripping automated endothelial keratoplasty (DSAEK) | no estimate extracted | NR | Low |
Severe visual loss (LogMAR BCVA of 1.0 or more) within 12 months' Descemet’s membrane endothelial keratoplasty (DMEK) vs Descemet’s stripping automated endothelial keratoplasty (DSAEK) | no estimate extracted | NR | Very low |
Endothelial cell count cells/mm2, 12 months' Descemet’s membrane endothelial keratoplasty (DMEK) vs Descemet’s stripping automated endothelial keratoplasty (DSAEK) | no estimate extracted | NR | Very low |
Corneal graft rejection any time pointa Descemet’s membrane endothelial keratoplasty (DMEK) vs Descemet’s stripping automated endothelial keratoplasty (DSAEK) | no estimate extracted | NR | Very low |
Primary graft failure any time pointa Descemet’s membrane endothelial keratoplasty (DMEK) vs Descemet’s stripping automated endothelial keratoplasty (DSAEK) | no estimate extracted | NR | Very low |
Corneal graft dislocation any time pointa Descemet’s membrane endothelial keratoplasty (DMEK) vs Descemet’s stripping automated endothelial keratoplasty (DSAEK) | RR 5.4 [1.51, 19.27] | NR | Low |