Hearing ‐ return to normal *Ventilation tubes versus laser myringotomy (6 to 12 months ‐ medium‐term) Adjusted for non‐independence of within‐individual measurements Assumed ICC of 0.5 № of participants: 132 (2 RCTs) · children aged 6 months to 12 years with otitis media with effusion (OME)
It is very uncertain whether early ventilation tubes changes hearing ‐ return to normal hearing Randomised by child compared with watchful waiting (treatment later if required) (very low certainty).
1 finding from 1 review
RR 0.98 [0.94, 1.03]
Studies not reported
Very low
Disease‐specific quality of life · children aged 6 months to 12 years with otitis media with effusion (OME)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Presence/persistence of OME · children aged 6 months to 12 years with otitis media with effusion (OME)
It is very uncertain whether early ventilation tubes changes presence/persistence of OME Randomised by child compared with watchful waiting (treatment later if required) (very low certainty).
1 finding from 1 review
RR 1.21 [0.84, 1.74]
Studies not reported
Very low
Adverse event: persistent perforation · children aged 6 months to 12 years with otitis media with effusion (OME)
It is very uncertain whether early ventilation tubes changes adverse event: persistent perforation compared with watchful waiting (treatment later if required) (very low certainty).
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Death by AKI aetiology: non‐surgical causes · AKI
Subgroup analyses: early showed no clear difference in death by AKI aetiology: non‐surgical causes compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).
1 finding from 1 review
Death by AKI aetiology: surgical causes · AKI
Subgroup analyses: early showed no clear difference in death by AKI aetiology: surgical causes compared with standard initiation of kidney replacement therapy (KRT) (low certainty).
1 finding from 1 review
Kidney recovery functionby KRT: continuous KRT · AKI
Subgroup analyses: early showed no clear difference in kidney recovery functionby KRT: continuous KRT compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).
1 finding from 1 review
Kidney recovery functionby KRT: continuous and intermittent KRT · AKI
Subgroup analyses: early showed no clear difference in kidney recovery functionby KRT: continuous and intermittent KRT compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).
1 finding from 1 review
Mortality ( · small asymptomatic AAA
Early endovascular repair showed no clear difference in mortality ( compared with ultrasound surveillance (low certainty).
1 finding from 1 review
Costs · small asymptomatic AAA
Early endovascular repair showed no clear difference in costs ( compared with ultrasound surveillance (low certainty).
2 findings from 1 review
QoL · small asymptomatic AAA
1 finding from 1 review
Aneurysm rupture ( · small asymptomatic AAA
1 finding from 1 review
Global state: average score: long term (+ 26 weeks) Global Assessment Scale (GAS). Scale from: 0 to 100. · patients with schizophrenia
1 finding from 1 review
Mental state · patients with schizophrenia
1 finding from 1 review
Adverse effects: tardive dyskinesia: long term (+ 26 weeks) as defined in each study · patients with schizophrenia
INTERMITTENT (EARLY‐BASED) showed no clear difference in adverse effects: tardive dyskinesia: long term (+26 weeks) as… compared with MAINTENANCE THERAPY (low certainty).
1 finding from 1 review
Cost‐effectiveness · patients with schizophrenia
1 finding from 1 review
Relapse · patients with schizophrenia
INTERMITTENT (EARLY‐BASED) may leads to higher relapse: long term (+ 26 weeks) as defined in each study compared with MAINTENANCE THERAPY (low certainty).
1 finding from 1 review
Hospital admissions · patients with schizophrenia
INTERMITTENT (EARLY‐BASED) probably leads to higher hospitalisation: long term (+ 26 weeks) as defined in each study compared with MAINTENANCE THERAPY (moderate certainty).
1 finding from 1 review
Complications
It is very uncertain whether early postoperative feeding changes complications compared with standard management (very low certainty).
1 finding from 1 review
Length of hospital stay
1 finding from 1 review