Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

2,112 questions in 171 reviews · Eyes and Vision

current versions
No studies 587 · 27.8%Ungraded 95 · 4.5%Very low 446 · 21.1%Low 557 · 26.4%Moderate 361 · 17.1%High 66 · 3.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Aqueous shunts with vs without mitomycin C
Proportion of participants with an adverse event · adults with glaucoma requiring aqueous shunt surgery
Aqueous shunts with mitomycin C versus aqueous shunts alone for glaucoma (2019) · Cochrane
no estimate extracted2 studies · 85 participantsLow
Endoscopic cyclophotocoagulation vs the Ahmed drainage implant
Pain control change from baseline 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extractedNRNo studies
Micropulse vs continuous‐wave cyclophotocoagulation
Mean change in best‐corrected visual acuity measured by logMAR 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted1 study · 48 participantsUngraded
Micropulse vs continuous‐wave cyclophotocoagulation
Mean change in the mean deviation in study eyes change from baseline 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extractedNRNo studies
Micropulse vs continuous‐wave cyclophotocoagulation
Mean number of glaucoma medications 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted1 study · 46 participantsUngraded
Micropulse vs continuous‐wave cyclophotocoagulation
Adverse events 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted1 study · 46 participantsUngraded
Micropulse vs continuous‐wave cyclophotocoagulation
Mean change in quality of life scores 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Pain control change from baseline 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Mean change in IOP measured in mmHg 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted1 study · 95 participantsLow
Intervention NR
Mean change in best‐corrected visual acuity measured by logMAR 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted2 studies · 127 participantsVery low
Intervention NR
Mean change in the mean deviation in study eyes change from baseline 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Mean number of glaucoma medications 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extractedNRNo studies
Endoscopic cyclophotocoagulation vs the Ahmed drainage implant
Mean change in IOP measured in mmHg 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted1 study · 58 participantsLow
Intervention NR
Adverse events 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Mean change in quality of life scores 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Pain control change from baseline 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted1 study · 50 participantsVery low
Intervention NR
Mean change in IOP measured in mmHg 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted1 study · 89 participantsUngraded
Intervention NR
Mean change in best‐corrected visual acuity measured by logMAR 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted1 study · 60 participantsVery low
Intervention NR
Mean change in the mean deviation in study eyes change from baseline 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Mean number of glaucoma medications 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted1 study · 50 participantsVery low
Intervention NR
Adverse events 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted1 study · 50 participantsUngraded
Intervention NR
Mean change in quality of life scores 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extractedNRNo studies
Endoscopic cyclophotocoagulation vs the Ahmed drainage implant
Mean change in best‐corrected visual acuity measured by logMAR 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted1 study · 54 participantsVery low
Endoscopic cyclophotocoagulation vs the Ahmed drainage implant
Mean change in mean deviation in study eyes 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extractedNRNo studies
Endoscopic cyclophotocoagulation vs the Ahmed drainage implant
Mean number of glaucoma medications 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted1 study · 54 participantsVery low
Endoscopic cyclophotocoagulation vs the Ahmed drainage implant
Adverse events 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted1 study · 68 participantsVery low
Endoscopic cyclophotocoagulation vs the Ahmed drainage implant
Mean change in quality of life scores 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extractedNRNo studies
Micropulse vs continuous‐wave cyclophotocoagulation
Pain control change from baseline 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted1 study · 44 participantsUngraded
Micropulse vs continuous‐wave cyclophotocoagulation
Mean change in IOP measured in mmHg 12 months postintervention · adults with refractory glaucoma
Cyclodestructive procedures for refractory glaucoma (2019) · Cochrane
no estimate extracted1 study · 48 participantsUngraded
Gore‐Tex vs Ethibond
Functional success of the surgery · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
RR 1.12 [0.93, 1.35]1 study · 60 participantsLow
Autogenous fascia vs Gore‐Tex
Sling removal · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
no estimate extracted1 study · 110 participantsLow
Autogenous fascia vs Gore‐Tex
Infection · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
RR 0.5 [0.04, 4.78]1 study · 110 participantsLow
Autogenous fascia vs Gore‐Tex
Ocular and systemic complications · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
RR 0.43 [0.11, 1.5]1 study · 110 participantsLow
Autogenous fascia vs Gore‐Tex
Economic outcomes ‐ not measured · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
no estimate extractedNRNo studies
Autogenous fascia vs Gore‐Tex
Quality of life ‐ not measured · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
no estimate extractedNRNo studies
Mersilene mesh vs autogenous fascia
Functional success of surgery ‐ not reported · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
no estimate extractedNRNo studies
Mersilene mesh vs autogenous fascia
Recurrence after surgery · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
no estimate extracted1 study · 31 participantsVery low
Mersilene mesh vs autogenous fascia
Sling removal ‐ not reported · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
no estimate extractedNRNo studies
Mersilene mesh vs autogenous fascia
Infection ‐ not reported · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
no estimate extractedNRNo studies
Mersilene mesh vs autogenous fascia
Ocular and systemic complications · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
no estimate extracted1 study · 31 participantsVery low
Gore‐Tex vs Ethibond
Recurrence after surgery · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
RR 0.33 [0.01, 6.64]1 study · 60 participantsLow
Mersilene mesh vs autogenous fascia
Economic outcomes ‐ not reported · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
no estimate extractedNRNo studies
Mersilene mesh vs autogenous fascia
Quality of life ‐ not reported · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
no estimate extractedNRNo studies
Gore‐Tex vs Ethibond
Sling removal · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
RR 0.2 [0.01, 3.37]1 study · 60 participantsLow
Gore‐Tex vs Ethibond
Infection · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
RR 1 [0.14, 5.28]1 study · 60 participantsLow
Gore‐Tex vs Ethibond
Ocular and systemic complications · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
no estimate extracted1 study · 60 participantsLow
Gore‐Tex vs Ethibond
Economic outcomes ‐ not measured · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
no estimate extractedNRNo studies
Gore‐Tex vs Ethibond
Quality of life ‐ not measured · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
no estimate extractedNRNo studies
Autogenous fascia vs Gore‐Tex
Functional success · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
RR 0.79 [0.62, 1.02]1 study · 110 participantsLow
Autogenous fascia vs Gore‐Tex
Recurrence after surgery · frontalis sling surgery for congenital ptosis
Types of materials for frontalis sling surgery for congenital ptosis (2019) · Cochrane
RR 0.5 [0.12, 1.8]1 study · 110 participantsLow