Cochrane · systematic review · CD011875

Aqueous shunts with mitomycin C versus aqueous shunts alone for glaucoma

Foo, VHX, Htoon, HM, Welsbie, DS, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
2
No studies
5
Included studies
NR
No studies 5 · 71.4%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 28.6%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Aqueous shunts with versus without mitomycin C for glaucoma

Population: adults with glaucoma requiring aqueous shunt surgery
7 questions
OutcomeEffectEvidenceStatus / GRADE
Mean IOP (mmHg)
Aqueous shunts with vs without mitomycin C
no estimate extracted3 studies · 78 participantsLow
Downgraded: risk of bias, imprecision
Control of IOP, assessed as the mean decrease in IOP from baseline
Aqueous shunts with vs without mitomycin C
no estimate extractedNRNo studies
Mean change from baseline in visual acuity
Aqueous shunts with vs without mitomycin C
no estimate extractedNRNo studies
Proportion of participants with stable best‐corrected visual acuity
Aqueous shunts with vs without mitomycin C
no estimate extractedNRNo studies
Proportion of participants with decreased visual acuity
Aqueous shunts with vs without mitomycin C
no estimate extractedNRNo studies
Proportion of participants with a postoperative hypertensive phase
Aqueous shunts with vs without mitomycin C
no estimate extractedNRNo studies
Proportion of participants with an adverse event
Aqueous shunts with vs without mitomycin C
no estimate extracted2 studies · 85 participantsLow
Downgraded: risk of bias, imprecision