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Evidence found and GRADE certainty

2,289 questions · 2,331 findings · 195 reviews · Pregnancy and Childbirth

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No studies found 480 · 20.6%GRADE not reported 288 · 12.4%Very low 467 · 20%Low 630 · 27%Moderate 338 · 14.5%High 128 · 5.5%

Technique of BP measurement: Korotkoff phase IV vs Korotkoff phase V to represent diastolic BP

Perinatal mortality · pregnant women with diastolic hypertension

Technique of BP measurement: Korotkoff phase IV showed no clear difference in perinatal mortality compared with korotkoff phase V to represent diastolic BP (low certainty).

1 finding from 1 review

Cervical cerclage in combination with antibiotics and tocolytics vs cervical cerclage

Serious neonatal morbidity

It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes serious neonatal morbidity (Reported in Miller 2014 as 'composite… compared with cervical cerclage alone (very low certainty).

1 finding from 1 review

Cervical cerclage in combination with antibiotics and tocolytics vs cervical cerclage

Preterm birth less than 34 weeks' gestation

It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes preterm birth < 34 completed weeks of pregnancy compared with cervical cerclage alone (very low certainty).

1 finding from 1 review

Oxytocin vs ergot alkaloids

Diastolic blood pressure > 100 mm Hg between delivery of the baby and discharge from the labour ward · women in the third stage of labour

Oxytocin showed no clear difference in diastolic blood pressure > 100 mm Hg between delivery of the baby… compared with ergot alkaloids (low certainty).

1 finding from 1 review

Intervention not reported

Preterm birth < 34 weeks · women carrying twins, asymptomatic for PTL or PPROM

It is very uncertain whether the intervention changes preterm birth < 34 weeks (very low certainty).

1 finding from 1 review

Metformin vs insulin

Hypertensive disorders of pregnancy (pregnancy‐induced hypertension) · women with type 2 diabetes

Maternal outcomes: oral anti‐diabetic agent (metformin) may leads to lower hypertensive disorders of pregnancy: pregnancy‐induced hypertension compared with insulin (low certainty).

1 finding from 1 review

Immediate vs deferred delivery of the preterm baby with suspected fetal compromise

Extended perinatal mortality · pregnant women at less than 36 weeks' gestation in whom there is clinical suspicion of fetal compromise

Immediate showed no clear difference in extended perinatal mortality compared with deferred delivery of the preterm baby with suspected fetal compromise (moderate certainty).

1 finding from 1 review

Immediate vs deferred delivery of the preterm baby with suspected fetal compromise

Death or disability at or after 2 years · pregnant women at less than 36 weeks' gestation in whom there is clinical suspicion of fetal compromise

Immediate showed no clear difference in death or disability at or after 2 years compared with deferred delivery of the preterm baby with suspected fetal compromise (moderate certainty).

1 finding from 1 review

Immediate vs deferred delivery of the preterm baby with suspected fetal compromise

Caesarean section · pregnant women at less than 36 weeks' gestation in whom there is clinical suspicion of fetal compromise

Immediate leads to higher caesarean section compared with deferred delivery of the preterm baby with suspected fetal compromise (high certainty).

1 finding from 1 review