Participant‐reported pain relief of 30% or greater · children and adolescents with chronic non‐cancer pain
1 finding from 1 review
Participant‐reported pain relief of 50% or greater · children and adolescents with chronic non‐cancer pain
1 finding from 1 review
Patient Global Impression of Change much or very much improved · children and adolescents with chronic non‐cancer pain
1 finding from 1 review
Time to feeding after surgery · Children up to 13 years of age, undergoing cleft lip repair surgery
The review found no eligible studies for this question.
1 finding from 1 review
Analgesia durationTime duration from the end of surgery to the time of first analgesic consumption. Scale from: 0 to 100. · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review
Heart rate, respiratory rate, and blood pressure · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review
Ahuja 1994: no significant difference in heart rate, respiratory rate, and blood pressure between groups. Takmaz 2009: no differences in respiratory rate and blood pressure, but children in the placebo group had…
2 studies
GRADE not reported
Duration of postoperative analgesia · Children up to 13 years of age, undergoing cleft lip repair surgery
It is very uncertain whether perioperative infraorbital nerve block changes duration of postoperative analgesia (in hours) compared with placebo (sham block) (very low certainty).
1 finding from 1 review
Pain measured by valid instruments (mean postoperative pain score) · Children up to 13 years of age, undergoing cleft lip repair surgery
It is very uncertain whether perioperative infraorbital nerve block changes pain measured by valid instruments (mean postoperative pain score) compared with placebo (sham block) (very low certainty).
1 finding from 1 review
Need for analgesic prescription for pain (supplemental analgesic requirements) · Children up to 13 years of age, undergoing cleft lip repair surgery
Perioperative infraorbital nerve block may leads to lower need for analgesic prescription for pain (supplemental analgesic… compared with placebo (sham block) (low certainty).
1 finding from 1 review
Pain‐free response at 2 h for moderate to severe baseline pain · adults with migraine headache ‐ moderate or severe and mild baseline pain
1 finding from 1 review
no estimate extracted
Studies not reported
High
Pain‐free response at 2 h for mild baseline pain · adults with migraine headache ‐ moderate or severe and mild baseline pain
1 finding from 1 review
no estimate extracted
Studies not reported
High
Headache relief at 2 h for moderate to severe baseline pain · adults with migraine headache ‐ moderate or severe and mild baseline pain
1 finding from 1 review
no estimate extracted
Studies not reported
High
Sustained pain‐free during the 24 h post dose for moderate to severe baseline pain · adults with migraine headache ‐ moderate or severe and mild baseline pain
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Sustained pain‐free during the 24 h post dose for mild baseline pain · adults with migraine headache ‐ moderate or severe and mild baseline pain
1 finding from 1 review
no estimate extracted
Studies not reported
High
Sustained headache relief during the 24 h post dose for moderate or severe baseline pain · adults with migraine headache ‐ moderate or severe and mild baseline pain
1 finding from 1 review
no estimate extracted
Studies not reported
High
At least 1 AE during treatment for moderate to severe baseline pain · adults with migraine headache ‐ moderate or severe and mild baseline pain
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
At least 1 AE during treatment for mild baseline pain · adults with migraine headache ‐ moderate or severe and mild baseline pain
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Serious AE (all levels of baseline pain) · adults with migraine headache ‐ moderate or severe and mild baseline pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients undergoing knee arthroscopy
3 findings from 1 review
no estimate extracted
7 studies · 297 participants
Low
no estimate extracted
7 studies · 297 participants
Low
no estimate extracted
7 studies · 297 participants
Low
Analgesia durationTime duration from the end of surgery to the time of first analgesic consumption. Scale from: 0 to 100. · patients undergoing knee arthroscopy
1 finding from 1 review