Maternal adverse effects of therapy · women at risk of preterm birth
Dexamethasone showed no clear difference in maternal adverse effects of therapy compared with betamethasone – maternal outcomes (moderate certainty).
1 finding from 1 review
Surgical assessment/satisfaction score = 1 or 2 (Technically successful procedure as defined by trial authors) · health problem or population
Summary of findings table ‐ Remifentanil may leads to higher surgical assessment/satisfaction score = 1 or 2 (Technically… compared with diazepam (low certainty).
1 finding from 1 review
Maternal respiratory rate (Maternal respiratory depression as defined by trial authors or measured using intraoperative maternal arterial oxygen saturation and maternal respiratory rate) · health problem or population
1 finding from 1 review
Maternal OAA score (observer assessment of alertness/sedation) < 4 (Maternal sedation measured using sedation scores as defined by authors) · health problem or population
Summary of findings table ‐ Remifentanil may leads to lower maternal OAA score (observer assessment of alertness/sedation) < 4… compared with diazepam (low certainty).
1 finding from 1 review
Perinatal mortality · health problem or population
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time taken to perform procedure · health problem or population
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Neonatal death (baby born alive at any gestation and dies within 28 days) · infants born of women at risk of preterm birth
Neonatal and child outcomes: corticosteroids leads to lower neonatal death (infants born with signs of life who die within the… compared with placebo or no treatment (high certainty).
1 finding from 1 review
RR 0.78 [0.7, 0.87]
Studies not reported
High
Respiratory distress syndrome · infants born of women at risk of preterm birth
Neonatal and child outcomes: corticosteroids leads to lower respiratory distress syndrome№ of participants: 11,183(26 RCTs) compared with placebo or no treatment (high certainty).
1 finding from 1 review
RR 0.71 [0.65, 0.78]
Studies not reported
High
Intraventricular haemorrhage · infants born of women at risk of preterm birth
Neonatal and child outcomes: corticosteroids probably leads to lower intraventricular haemorrhage (IVH)№ of participants: 8475(12 RCTs) compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
RR 0.58 [0.45, 0.75]
Studies not reported
Moderate
Mean birthweight · infants born of women at risk of preterm birth
1 finding from 1 review
no estimate extracted
Studies not reported
High
Developmental delay in childhood№ of participants: 600 (3 RCTs). Age at · infants born of women at risk of preterm birth
Neonatal and child outcomes: corticosteroids probably leads to lower developmental delay in childhood№ of participants: 600 (3 RCTs). Age… compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
RR 0.51 [0.27, 0.97]
Studies not reported
Moderate
Maternal death · women at risk of preterm birth
Maternal outcomes: corticosteroids showed no clear difference in maternal death compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
RR 1.19 [0.36, 3.89]
Studies not reported
Moderate
Chorioamnionitis · women at risk of preterm birth
Maternal outcomes: corticosteroids showed no clear difference in chorioamnionitis№ of participants: 8374(15 RCTs) compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
RR 0.86 [0.69, 1.08]
Studies not reported
Moderate
Endometritis · women at risk of preterm birth
Maternal outcomes: corticosteroids showed no clear difference in endometritis№ of participants: 6764(10 RCTs) compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
RR 1.14 [0.82, 1.58]
Studies not reported
Moderate
Preterm birth · women with singleton pregnancies and threatened preterm labor (PTL) between 23 to 35 weeks
Main comparison (FFN knowledge showed no clear difference in preterm birth < 37 weeks compared with no knowledge) (low certainty).
1 finding from 1 review
Preterm birth less than 34 weeks' gestation · women with singleton pregnancies and threatened preterm labor (PTL) between 23 to 35 weeks
Main comparison (FFN knowledge showed no clear difference in preterm birth < 34 weeks compared with no knowledge) (low certainty).
1 finding from 1 review
Preterm birth < 32 weeks · women with singleton pregnancies and threatened preterm labor (PTL) between 23 to 35 weeks
It is very uncertain whether main comparison (FFN knowledge changes preterm birth < 32 weeks compared with no knowledge) (very low certainty).
1 finding from 1 review
Maternal hospitalization · women with singleton pregnancies and threatened preterm labor (PTL) between 23 to 35 weeks
Main comparison (FFN knowledge showed no clear difference in maternal hospitalization compared with no knowledge) (low certainty).
1 finding from 1 review
Perinatal death or severe morbidity · women with non‐reassuring FHR tracing during labour or induction of labour
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Caesarean section · women with non‐reassuring FHR tracing during labour or induction of labour
Summary of findings for IV terbutaline showed no clear difference in caesarean delivery compared with IV nitroglycerin (low certainty).
1 finding from 1 review