Cochrane · systematic review · CD006843

Fetal fibronectin testing for reducing the risk of preterm birth

Berghella, V, Saccone, G · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 25%Low 3 · 75%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Main comparison (FFN knowledge versus no knowledge)

Population: women with singleton pregnancies and threatened preterm labor (PTL) between 23 to 35 weeks
4 questions
OutcomeEffectEvidenceStatus / GRADE
Preterm birth < 37 weeks
Main comparison (FFN knowledge vs no knowledge)
RR 0.72 [0.52, 1.01]5 studies · 434 participantsLow
Downgraded: risk of bias, imprecision
Preterm birth < 34 weeks
Main comparison (FFN knowledge vs no knowledge)
RR 1.09 [0.54, 2.18]4 studies · 357 participantsLow
Downgraded: risk of bias, imprecision
Preterm birth < 32 weeks
Main comparison (FFN knowledge vs no knowledge)
RR 0.79 [0.16, 3.96]4 studies · 357 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Maternal hospitalization
Main comparison (FFN knowledge vs no knowledge)
RR 1.06 [0.79, 1.43]5 studies · 441 participantsLow
Downgraded: risk of bias, imprecision