Development of endocarditis due to other (non-dental) causes · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive dental procedure
The review found no eligible studies for this question.
1 finding from 1 review
Development of endocarditis (in those with definite indication for prophylaxis) · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive dental procedure
It is very uncertain whether antibiotic prophylaxis before dental procedure changes development of endocarditis (in those with definite indication for… compared with no antibiotic prophylaxis or placebo (very low certainty).
1 finding from 1 review
Clinical outcomes · respiratory infections
1 finding from 1 review
Duration of clinical outcomes (pain, malaise, fever) · respiratory infections
1 finding from 1 review
Clinical outcomes: pain, malaise, fever · respiratory infections
1 finding from 1 review
Duration of clinical outcomes (pain, malaise, fever) · respiratory infections
1 finding from 1 review
Neonatal mortality · neonates with possible serious bacterial infection
Comparison 2: any simplified antibiotic regimen showed no clear difference in neonatal mortality compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).
1 finding from 1 review
Treatment failure · neonates with possible serious bacterial infection
Comparison 2: any simplified antibiotic regimen showed no clear difference in treatment failure compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).
1 finding from 1 review
Adverse events · neonates with possible serious bacterial infection
Comparison 2: any simplified antibiotic regimen showed no clear difference in adverse events compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).
1 finding from 1 review
Prophylactic antibiotic at one dose or duration vs Same antibiotic at a different dose or duration
Outcome not reported · Adults undergoing dental implant placement
1 finding from 1 review
No conclusive information can be derived from the only trial that compared three different durations of antibiotic prophylaxis, since no event (implant or prosthesis failures, infections or adverse events) occurred in…
1 study · 100 participants
GRADE not reported
Prosthesis failure · Adults undergoing dental implant placement
Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in prosthesis failure compared with no antibiotics or placebo; GRADE not reported.
1 finding from 1 review
Postoperative infection · Adults undergoing dental implant placement
Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in postoperative infection compared with no antibiotics or placebo; GRADE not reported.
1 finding from 1 review
Implant failure · Adults undergoing dental implant placement
Prophylactic systemic antibiotics (amoxicillin) probably leads to lower implant failure compared with no antibiotics or placebo (moderate certainty).
1 finding from 1 review
Adverse events · Adults undergoing dental implant placement
Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in adverse events compared with no antibiotics or placebo; GRADE not reported.
1 finding from 1 review
No cure ‐ all trials · patients with asymptomatic bacteriuria during pregnancy
It is very uncertain whether single‐dose antibiotic changes no cure ‐ all trials compared with short‐course (four‐ to seven‐day) antibiotic (very low certainty).
1 finding from 1 review
Recurrent asymptomatic bacteriuria ‐ all trials · patients with asymptomatic bacteriuria during pregnancy
It is very uncertain whether single‐dose antibiotic changes recurrent asymptomatic bacteriuria ‐ all trials compared with short‐course (four‐ to seven‐day) antibiotic (very low certainty).
1 finding from 1 review
Pyelonephritis ‐ Same antimicrobial agent only4 · patients with asymptomatic bacteriuria during pregnancy
It is very uncertain whether single‐dose antibiotic changes pyelonephritis ‐ Same antimicrobial agent only4 compared with short‐course (four‐ to seven‐day) antibiotic (very low certainty).
1 finding from 1 review
Low birthweight ‐ Same antimicrobial agent only · patients with asymptomatic bacteriuria during pregnancy
Single‐dose antibiotic leads to higher low birthweight ‐ Same antimicrobial agent only compared with short‐course (four‐ to seven‐day) antibiotic (high certainty).
1 finding from 1 review
Preterm delivery ‐ Same antimicrobial agent only · patients with asymptomatic bacteriuria during pregnancy
Single‐dose antibiotic showed no clear difference in preterm delivery ‐ Same antimicrobial agent only compared with short‐course (four‐ to seven‐day) antibiotic (moderate certainty).
1 finding from 1 review
Side effects ‐ all trials · patients with asymptomatic bacteriuria during pregnancy
Single‐dose antibiotic may leads to lower side effects ‐ all trials compared with short‐course (four‐ to seven‐day) antibiotic (low certainty).
1 finding from 1 review