Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Local anaesthetic injection vs no treatment/placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · septal surgery

The review found no eligible studies for this question.

3 findings from 1 review

Local anaesthetic application via nasal packing vs no packing/packing with placebo

Additional analgesia required (escape analgesia) · septal surgery

Local anaesthetic application via nasal packing probably leads to lower requirement for additional analgesia compared with no packing/packing with placebo (moderate certainty).

1 finding from 1 review

Sphenopalatine ganglion block vs no treatment/placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · septal surgery

The review found no eligible studies for this question.

3 findings from 1 review

Intervention not reported

Adverse perinatal outcome (composite outcome including stillbirth, neonatal death, and major neonatal morbidity) · women with a previous stillbirth of > 20 weeks' gestation who are pregnant or considering a subsequent pregnancy

It is very uncertain whether the intervention changes adverse perinatal outcome (composite outcome including stillbirth,… (very low certainty).

1 finding from 1 review