Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,747 questions · 3,943 findings · 594 reviews

No studies found 784 · 19.9%GRADE not reported 530 · 13.4%Very low 1,040 · 26.4%Low 981 · 24.9%Moderate 444 · 11.3%High 164 · 4.2%

Toric intraocular lens (IOL) vs limbal relaxing incisions (LRIs)

Spectacle independence for distance as reported by the participant · people with astigmatism who are having cataract surgery (phacoemulsification)

Toric intraocular lens (IOL) may leads to higher spectacle independence for distance as reported by the participant compared with limbal relaxing incisions (LRIs) (low certainty).

1 finding from 1 review

Hyperbaric oxygen vs No HBO therapy

Preimplantation complications · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

Hyperbaric oxygen (HBO) therapy led to lower preimplantation complications compared with no HBO therapy; GRADE not reported.

1 finding from 1 review

Hyperbaric oxygen vs No HBO therapy

Prosthetic failure (2 years) · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

It is very uncertain whether hyperbaric oxygen (HBO) therapy changes prosthetic failure compared with no HBO therapy (very low certainty).

1 finding from 1 review

Hyperbaric oxygen vs No HBO therapy

Overall denture satisfaction (0-10 scale) · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

Hyperbaric oxygen (HBO) therapy showed no clear difference in patient satisfaction (overall denture satisfaction) compared with no HBO therapy; GRADE not reported.

1 finding from 1 review

Hyperbaric oxygen vs No HBO therapy

Cost‐effectiveness · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

The review found no eligible studies for this question.

1 finding from 1 review

Hyperbaric oxygen vs No HBO therapy

Implant failure · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

Hyperbaric oxygen (HBO) therapy showed no clear difference in implant failure compared with no HBO therapy; GRADE not reported.

1 finding from 1 review

Hyperbaric oxygen vs No HBO therapy

Postimplantation complications · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

Hyperbaric oxygen (HBO) therapy showed no clear difference in postimplantation complications compared with no HBO therapy; GRADE not reported.

1 finding from 1 review

Hyperbaric oxygen vs control without HBOT

Death at 1 year · any person with radiation tissue injury arising later than 6 months after irradiation (LRTI), including dysfunction or necrosis of any…

Hyperbaric oxygen therapy (HBOT) showed no clear difference in death at 1 year compared with control without HBOT (low certainty).

1 finding from 1 review

Hyperbaric oxygen vs control without HBOT

Complete or substantial improvement of condition · any person with radiation tissue injury arising later than 6 months after irradiation (LRTI), including dysfunction or necrosis of any…

Hyperbaric oxygen therapy (HBOT) may leads to higher complete or substantial improvement of condition compared with control without HBOT (low certainty).

1 finding from 1 review

Hyperbaric oxygen vs control without HBOT

Visual disturbances · any person with radiation tissue injury arising later than 6 months after irradiation (LRTI), including dysfunction or necrosis of any…

Hyperbaric oxygen therapy (HBOT) leads to higher visual disturbances compared with control without HBOT (high certainty).

1 finding from 1 review