Question · asked by 1 review

Autologous platelet‐rich plasma vs placebo or usual care: Adverse events

Population
adults with chronic wounds
Intervention
Autologous platelet‐rich plasma
Comparison
placebo or usual care
Outcome
Adverse events

It is very uncertain whether autologous platelet‐rich plasma changes adverse events compared with standard care with/without placebo (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Autologous platelet‐rich plasma vs standard care with/without placebo
Adverse events · adults with chronic wounds
It is very uncertain whether autologous platelet‐rich plasma changes adverse events compared with standard care with/without placebo (very low certainty).
Autologous platelet‐rich plasma for treating chronic wounds (2016) · Cochrane Headline outcomes only
RR 1.05 [0.29, 3.88]3 studies · 102 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Autologous platelet‐rich plasma for treating chronic wounds
2016 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.