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Evidence found and GRADE certainty

949 questions · 1,008 findings · 130 reviews · Gynaecology and Fertility

No studies found 195 · 19.3%GRADE not reported 30 · 3%Very low 346 · 34.3%Low 323 · 32%Moderate 101 · 10%High 13 · 1.3%

Ultrasound‐guided transvaginal ovarian needle drilling with gonadotropin (Gn) vs Gn

Multiple pregnancy rate · clomiphene‐resistant polycystic ovarian syndrome in subfertile women

It is very uncertain whether ultrasound‐guided transvaginal ovarian needle drilling with… changes multiple pregnancy rate (per woman) compared with gn (very low certainty).

1 finding from 1 review

Recombinant follicle stimulating hormone vs urinary‐derived gonadotrophins

Multiple pregnancy rate · ovulation induction in polycystic ovarian syndrome

Recombinant follicle stimulating hormone showed no clear difference in incidence of multiple pregnancy (per woman) compared with urinary‐derived gonadotrophins (low certainty).

1 finding from 1 review

Recombinant follicle stimulating hormone vs urinary‐derived gonadotrophins

Clinical pregnancy rate · ovulation induction in polycystic ovarian syndrome

Recombinant follicle stimulating hormone showed no clear difference in clinical pregnancy rate per woman compared with urinary‐derived gonadotrophins (low certainty).

1 finding from 1 review

Human menopausal gonadotrophin or highly purified human menopausal gonadotrophin vs urinary follicle stimulating hormone

Multiple pregnancy rate · ovulation induction in polycystic ovarian syndrome

It is very uncertain whether human menopausal gonadotrophin or highly purified human menopausal… changes incidence of multiple pregnancy (per woman) compared with urinary follicle stimulating hormone (very low certainty).

1 finding from 1 review

Human menopausal gonadotrophin or highly purified human menopausal gonadotrophin vs urinary follicle stimulating hormone

Clinical pregnancy rate · ovulation induction in polycystic ovarian syndrome

It is very uncertain whether human menopausal gonadotrophin or highly purified human menopausal… changes clinical pregnancy rate per woman compared with urinary follicle stimulating hormone (very low certainty).

1 finding from 1 review

Magnetic‐activated cell sorting (MACS) vs hyaluronic acid‐selected sperm (HA‐ICSI)

Miscarriage per clinical pregnancy · assisted reproduction

It is very uncertain whether magnetic‐activated cell sorting (MACS) changes miscarriage per clinical pregnancy compared with hyaluronic acid‐selected sperm (HA‐ICSI) (very low certainty).

1 finding from 1 review

Magnetic‐activated cell sorting (MACS) vs hyaluronic acid‐selected sperm (HA‐ICSI)

Clinical pregnancy · assisted reproduction

It is very uncertain whether magnetic‐activated cell sorting (MACS) changes clinical pregnancy per woman randomly assigned compared with hyaluronic acid‐selected sperm (HA‐ICSI) (very low certainty).

1 finding from 1 review

Hyaluronic acid‐selected sperm (HA‐ICSI) vs viscous medium containing HA (SpermSlow)

Miscarriage per clinical pregnancy · assisted reproduction

It is very uncertain whether hyaluronic acid‐selected sperm (HA‐ICSI) changes miscarriage per clinical pregnancy compared with viscous medium containing HA (SpermSlow) (very low certainty).

1 finding from 1 review

Hyaluronic acid‐selected sperm (HA‐ICSI) vs viscous medium containing HA (SpermSlow)

Clinical pregnancy · assisted reproduction

It is very uncertain whether hyaluronic acid‐selected sperm (HA‐ICSI) changes clinical pregnancy per woman randomly assigned compared with viscous medium containing HA (SpermSlow) (very low certainty).

1 finding from 1 review

Thyroxine vs placebo or no treatment

Adverse events including maternal pregnancy complications, foetal complications and adverse effects of thyroxine · subfertile women with euthyroid autoimmune thyroid disease or subclinical hypothyroidism

Thyroxine led to lower adverse events including maternal pregnancy complications, foetal… compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

TLS with conventional morphological assessment of still TLS images vs conventional incubation and assessment

Live birth or ongoing pregnancy · couples undergoing assisted reproductive technology

TLS with conventional morphological assessment of still TLS images showed no clear difference in live birth or ongoing pregnancy compared with conventional incubation and assessment (low certainty).

1 finding from 1 review