Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

550 questions · 669 findings · 42 reviews

No studies found 162 · 24.2%GRADE not reported 272 · 40.7%Very low 110 · 16.4%Low 93 · 13.9%Moderate 29 · 4.3%High 3 · 0.4%

Silver diamine fluoride (SDF) plus fluoride varnish vs Sealants plus fluoride varnish (with or without restorations)

Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review

Silver diamine fluoride (SDF) vs Glass ionomer cement (GIC) plus fluoride varnish

Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review

Silver diamine fluoride (SDF) vs Silver nitrate plus fluoride varnish

Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review

Silver diamine fluoride (SDF) vs placebo or no treatment

Adverse effects · Children and adults (with or without carious lesions)
2 findings from 1 review

Silver diamine fluoride (SDF) vs Fluoride varnish

Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review

Silver diamine fluoride (SDF) vs placebo or no treatment

Aesthetics · Children and adults (with or without carious lesions)
1 finding from 1 review

Silver diamine fluoride (SDF) vs Atraumatic restorative treatment (ART) with glass ionomer cement (GIC) or glass ionomer material

Aesthetics · Children and adults (with or without carious lesions)
1 finding from 1 review

SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)

Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review

Rubber/elastomeric cleaning stick plus toothbrushing vs Toothbrushing alone

Gingivitis · Adults, 16 years and older (dentate)

It is very uncertain whether rubber/elastomeric cleaning stick plus toothbrushing changes gingivitis (proportion of bleeding sites) compared with toothbrushing alone (very low certainty).

2 findings from 1 review

Rubber/elastomeric cleaning stick plus toothbrushing vs Flossing plus toothbrushing

Plaque · Adults, 16 years and older (dentate)

It is very uncertain whether rubber/elastomeric cleaning stick plus toothbrushing changes plaque compared with flossing plus toothbrushing (very low certainty).

1 finding from 1 review

Rubber/elastomeric cleaning stick plus toothbrushing vs Flossing plus toothbrushing

Gingivitis · Adults, 16 years and older (dentate)

It is very uncertain whether rubber/elastomeric cleaning stick plus toothbrushing changes gingivitis (gingival index) compared with flossing plus toothbrushing (very low certainty).

2 findings from 1 review

Wooden cleaning stick plus toothbrushing vs Toothbrushing alone

Gingivitis · Adults, 16 years and older (dentate)

The review found no eligible studies for this question.

2 findings from 1 review

Oral irrigation plus toothbrushing vs Flossing plus toothbrushing

Gingivitis · Adults, 16 years and older (dentate)

It is very uncertain whether oral irrigation plus toothbrushing changes gingivitis (gingival index) compared with flossing plus toothbrushing (very low certainty).

2 findings from 1 review

Oral irrigation plus toothbrushing vs Toothbrushing alone

Periodontitis (probing pocket depth) · Adults, 16 years and older (dentate)
1 finding from 1 review