Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,121 questions · 2,186 findings · 242 reviews

No studies found 493 · 22.6%GRADE not reported 158 · 7.2%Very low 600 · 27.4%Low 474 · 21.7%Moderate 364 · 16.7%High 97 · 4.4%

Oral antibiotics vs placebo

Measurements of eradication or decrease in numbers of colonies of positive cultures of bacteria · adult participants with chronic blepharitis

The review found no eligible studies for this question.

1 finding from 1 review

Oral antibiotics vs placebo

Adverse events at 1 month · adult participants with chronic blepharitis

It is very uncertain whether oral antibiotics changes adverse events at 1 month compared with placebo (very low certainty).

1 finding from 1 review

Oral antibiotics vs placebo

Economic costs and benefits of different interventions · adult participants with chronic blepharitis

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic treatment (benzathine penicillin) vs other antibiotics

Serological cure (4‐fold decrease or greater in non‐treponemal tests titre) · newborns with congenital syphilis

Antibiotic treatment (benzathine penicillin) showed no clear difference in serological cure (4‐fold decrease or greater in non‐treponemal tests… compared with any other antibiotic (procaine benzylpenicillin) (moderate certainty).

1 finding from 1 review

Antibiotic treatment (benzathine penicillin) vs other antibiotics

Absence of clinical manifestations of congenital syphilis during · newborns with congenital syphilis

Antibiotic treatment (benzathine penicillin) showed no clear difference in absence of clinical manifestations of congenital syphilis during compared with any other antibiotic (procaine benzylpenicillin) (high certainty).

1 finding from 1 review

Antibiotic prophylaxis before dental procedure vs placebo or no prophylaxis

Mortality or serious adverse events requiring hospital admission · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive dental procedure

The review found no eligible studies for this question.

1 finding from 1 review