Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,209 questions · 2,322 findings · 227 reviews · Headline outcomes only

No studies found 644 · 27.7%GRADE not reported 135 · 5.8%Very low 591 · 25.5%Low 582 · 25.1%Moderate 309 · 13.3%High 61 · 2.6%

Intervention not reported

No active intervention(2 RCTs, 256 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding

It is very uncertain whether the intervention changes no active intervention(2 RCTs, 256 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

No active intervention(2 RCTs, 208 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding

It is very uncertain whether the intervention changes no active intervention(2 RCTs, 208 participants) (very low certainty).

1 finding from 1 review

Oral iron sulphate vs oral iron hydroxide polymaltose complex

Serious adverse events ‐ active or inactive disease (14 days) · IBD patients

It is very uncertain whether oral iron sulphate changes serious adverse events ‐ active or inactive disease (14 days) compared with oral iron hydroxide polymaltose complex (very low certainty).

1 finding from 1 review

Lamotrigine vs lithium

Recurrence of any episodes at one year (active suicidal behavior) · bipolar disorder

It is very uncertain whether lamotrigine changes recurrence of any episodes at one year (active suicidal behavior) compared with lithium (very low certainty).

1 finding from 1 review