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Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

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No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Summary of findings table ‐ Intralesional classical immunosuppresants (betamethasone or triamcinolone) vs placebo

Short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of · adults with alopecia areata

It is very uncertain whether summary of findings table ‐ Intralesional classical… changes short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of compared with placebo (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Any type of hormonal contraception (estrogen plus progestin or progestin‐only) vs no contraception

Hospitalization · people with COVID‐19

It is very uncertain whether summary of findings table ‐ Any type of hormonal contraception… changes hospitalization compared with no contraception (very low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Electrocoagulation in combination with allopurinol or with dimethyl sulphoxide vs control (vehicle solution of allopurinol by mouth)

All‐cause mortality at last · people with liver metastases

Summary of Findings Table ‐ Electrocoagulation in combination with… may leads to lower all‐cause mortality at last compared with control (vehicle solution of allopurinol by mouth) (low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Electrocoagulation in combination with allopurinol or with dimethyl sulphoxide vs control (vehicle solution of allopurinol by mouth)

Post‐operative deaths · people with liver metastases

It is very uncertain whether summary of Findings Table ‐ Electrocoagulation in combination with… changes post‐operative deaths compared with control (vehicle solution of allopurinol by mouth) (very low certainty).

1 finding from 1 review

Summary of findings table (subcomparison 1): chemotherapy or targeted therapy plus best supportive care (BSC) vs BSC

Overall survival · palliative participants with esophageal and GE‐junction carcinoma

Summary of findings table (subcomparison 1): chemotherapy or… leads to lower overall survival compared with BSC (high certainty).

1 finding from 1 review

Summary of findings table (subcomparison 1): chemotherapy or targeted therapy plus best supportive care (BSC) vs BSC

Progression‐free survival · palliative participants with esophageal and GE‐junction carcinoma

It is very uncertain whether summary of findings table (subcomparison 1): chemotherapy or… changes progression‐free survival compared with BSC (very low certainty).

1 finding from 1 review

Summary of findings table (subcomparison 1): chemotherapy or targeted therapy plus best supportive care (BSC) vs BSC

Toxicity · palliative participants with esophageal and GE‐junction carcinoma

It is very uncertain whether summary of findings table (subcomparison 1): chemotherapy or… changes toxicity compared with BSC (very low certainty).

1 finding from 1 review

Summary of findings table (subcomparison 5): chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

Overall survival · palliative participants with AC of the esophagus

Summary of findings table (subcomparison 5): chemotherapy or… leads to lower overall survival compared with control intervention alone (high certainty).

1 finding from 1 review

Summary of findings table (subcomparison 5): chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

Progression‐free survival · palliative participants with AC of the esophagus

It is very uncertain whether summary of findings table (subcomparison 5): chemotherapy or… changes progression‐free survival compared with control intervention alone (very low certainty).

1 finding from 1 review

Summary of findings table (subcomparison 5): chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

Toxicity · palliative participants with AC of the esophagus

It is very uncertain whether summary of findings table (subcomparison 5): chemotherapy or… changes toxicity compared with control intervention alone (very low certainty).

1 finding from 1 review