Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,539 questions · 2,602 findings · 424 reviews · Headline outcomes only

No studies found 572 · 22%GRADE not reported 189 · 7.3%Very low 527 · 20.3%Low 685 · 26.3%Moderate 514 · 19.8%High 115 · 4.4%

Main comparison of patch angioplasty vs primary closure

Long‐term stroke or death · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…

It is very uncertain whether main comparison of patch angioplasty changes any stroke or death during long‐term compared with primary closure (very low certainty).

1 finding from 1 review

Main comparison of patch angioplasty vs primary closure

Restenosis (> 50%) or occlusion of operated artery during long‐term · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…

Main comparison of patch angioplasty may leads to lower restenosis (> 50%) or occlusion of operated artery during long‐term compared with primary closure (low certainty).

1 finding from 1 review

Intervention not reported

Secondary ‐ Long‐term complications during · Patients with acute uncomplicated diverticulitis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Secondary ‐ Long‐term emergency surgery during · Patients with acute uncomplicated diverticulitis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Secondary ‐ Long‐term complications during · Patients with acute uncomplicated diverticulitis

The intervention showed no clear difference in secondary ‐ Long‐term complications during (low certainty).

1 finding from 1 review

Intervention not reported

Secondary ‐ Long‐term emergency surgery during · Patients with acute uncomplicated diverticulitis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Secondary ‐ Long‐term complications during · Patients with acute uncomplicated diverticulitis

The intervention showed no clear difference in secondary ‐ Long‐term complications during (low certainty).

1 finding from 1 review

Intervention not reported

Secondary ‐ Long‐term emergency surgery during · Patients with acute uncomplicated diverticulitis

The intervention showed no clear difference in secondary ‐ Long‐term emergency surgery during (low certainty).

1 finding from 1 review

Topical clonidine (TC) vs placebo

Participant‐reported pain relief of 50% or greater · adults with painful diabetic neuropathy

Topical clonidine (TC) showed no clear difference in participant‐reported pain relief of 50% or greater during longest compared with placebo (low certainty).

1 finding from 1 review

Topical clonidine (TC) vs placebo

Participant‐reported pain relief of 30% or greater · adults with painful diabetic neuropathy

It is very uncertain whether topical clonidine (TC) changes participant‐reported pain relief of 30% or greater during longest compared with placebo (very low certainty).

1 finding from 1 review

Topical clonidine (TC) vs placebo

Patient Global Impression of Change much or very much improved · adults with painful diabetic neuropathy

Topical clonidine (TC) showed no clear difference in much or very much improved on PGIC during longest compared with placebo (low certainty).

1 finding from 1 review