Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

542 questions · 578 findings · 107 reviews

No studies found 32 · 5.5%GRADE not reported 76 · 13.1%Very low 155 · 26.8%Low 150 · 26%Moderate 144 · 24.9%High 21 · 3.6%

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Mastectomy skin flap necrosis (number of women with mastectomy skin flap necrosis within 30 days after surgery) · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes mastectomy skin flap necrosis (number of women with mastectomy skin… compared with clinical evaluation (very low certainty).

1 finding from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Infection (number of breasts with infection within 30 days after surgery) · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes infection (number of breasts with infection within 30 days after… compared with clinical evaluation (very low certainty).

1 finding from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Haematoma (number of breasts with haematoma within 30 days after surgery) · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes haematoma (number of breasts with haematoma within 30 days after… compared with clinical evaluation (very low certainty).

1 finding from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Seroma (30 days) · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes seroma (number of breast with seroma within 30 days after surgery) compared with clinical evaluation (very low certainty).

2 findings from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Reoperation · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes reoperation (number of women that were operated again within 30 days… compared with clinical evaluation (very low certainty).

2 findings from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Dehiscence · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes dehiscence (number of women with dehiscence within 30 days after… compared with clinical evaluation (very low certainty).

1 finding from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Infection (number of women with infection of the skin flap or implant within 30 days after surgery) · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes infection (number of women with infection of the skin flap or… compared with clinical evaluation (very low certainty).

1 finding from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Haematoma (proportion of participants in each group with haematoma; · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes haematoma (number of women with haematoma within 30 days after… compared with clinical evaluation (very low certainty).

1 finding from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Mastectomy skin flap necrosis (number of breasts with mastectomy skin flap necrosis within 30 days after surgery) · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes mastectomy skin flap necrosis (number of breasts with mastectomy… compared with clinical evaluation (very low certainty).

1 finding from 1 review

Delayed chemotherapy vs immediate chemotherapy

Nausea and vomiting · patients with asymptomatic, incurable, metastatic colorectal cancer

It is very uncertain whether delayed chemotherapy changes toxicity – nausea and vomiting compared with immediate chemotherapy (very low certainty).

1 finding from 1 review

Delayed chemotherapy vs immediate chemotherapy

Toxicity – stomatitis · patients with asymptomatic, incurable, metastatic colorectal cancer

It is very uncertain whether delayed chemotherapy changes toxicity – stomatitis compared with immediate chemotherapy (very low certainty).

1 finding from 1 review

Delayed chemotherapy vs immediate chemotherapy

Toxicity – diarrhoea · patients with asymptomatic, incurable, metastatic colorectal cancer

It is very uncertain whether delayed chemotherapy changes toxicity – diarrhoea compared with immediate chemotherapy (very low certainty).

1 finding from 1 review

TCu 220C vs Copper 7

Discontinuation due to pregnancy (750 days) · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to pregnancy (750 days) compared with copper 7 (moderate certainty).

1 finding from 1 review

TCu 220C vs Copper 7

Discontinuation due to expulsion (750 days) · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to expulsion (750 days) compared with copper 7 (moderate certainty).

1 finding from 1 review