Findings

What do systematic reviews say?

4,678 questions · 4,859 findings · 283 reviews

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No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone

All‐cause mortality · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis

The review found no eligible studies for this question.

1 finding from 1 review

Surgery for nasal polyposis in cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

'Summary of findings' table for primary outcomes: Taxation of sugar‐added foods vs no taxation

Mean expenditure on untaxed sugar‐added foods · general population

1 finding from 1 review

Taxation of unprocessed sugar or sugar‐added foods for reducing their consumption and preventing obesity or other… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40210 participants
Very low

'Summary of findings' table for primary outcomes: Taxation of sugar‐added foods vs no taxation

Difference in mean expenditure on taxed sugar‐added foods compared with untaxed sugar‐added foods · general population

1 finding from 1 review

Taxation of unprocessed sugar or sugar‐added foods for reducing their consumption and preventing obesity or other… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40210 participants
Very low

'Summary of findings' table for primary outcomes: Taxation of sugar‐added foods vs no taxation

Substitution: mean consumption (purchased quantities) of untaxed sugar‐added foods · general population

1 finding from 1 review

Taxation of unprocessed sugar or sugar‐added foods for reducing their consumption and preventing obesity or other… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40210 participants
Very low

'Summary of findings' table for primary outcomes: Taxation of sugar‐added foods vs no taxation

Substitution: difference in mean consumption (purchased quantities) of untaxed sugar‐added foods compared with untaxed sugar‐added foods · general population

1 finding from 1 review

Taxation of unprocessed sugar or sugar‐added foods for reducing their consumption and preventing obesity or other… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40210 participants
Very low

'Summary of findings' table for primary outcomes: Taxation of sugar‐added foods vs no taxation

Mean expenditure on taxed sugar‐added foods · general population

1 finding from 1 review

Taxation of unprocessed sugar or sugar‐added foods for reducing their consumption and preventing obesity or other… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40210 participants
Very low

Summary of findings 3: Efficacy and safety of IVT pegcetacoplan 4‐weekly (monthly) vs sham

Change in visual acuity (logMAR) ‐ 12 months (negative is better) · adults with GA due to AMD

1 finding from 1 review

Complement inhibitors for age‐related macular degeneration 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 164 participants
Moderate

Summary of findings 3: Efficacy and safety of IVT pegcetacoplan 4‐weekly (monthly) vs sham

Change in untransformed GA lesion size from baseline at 1 year (mmÂ²)Â · adults with GA due to AMD

1 finding from 1 review

Complement inhibitors for age‐related macular degeneration 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 967 participants
High

Summary of findings 3: Efficacy and safety of IVT pegcetacoplan 4‐weekly (monthly) vs sham

Safety: Development of macular neovascularisation or exudative AMD at 1 year · adults with GA due to AMD

Summary of findings 3: Efficacy and safety of IVT pegcetacoplan… showed no clear difference in safety: Development of macular neovascularisation or exudative AMD… compared with sham; GRADE not reported.

1 finding from 1 review

Complement inhibitors for age‐related macular degeneration 2023 · Cochrane Headline outcomes only
RR 4.47 [0.41, 48.98]
3 studies · 1003 participants
GRADE not reported

Summary of findings 3: Efficacy and safety of IVT pegcetacoplan 4‐weekly (monthly) vs sham

Safety: Development of endophthalmitis at 1 year · adults with GA due to AMD

Summary of findings 3: Efficacy and safety of IVT pegcetacoplan… showed no clear difference in safety: Development of endophthalmitis at 1 year compared with sham (moderate certainty).

1 finding from 1 review

Complement inhibitors for age‐related macular degeneration 2023 · Cochrane Headline outcomes only
RR 3.79 [0.42, 34.05]
3 studies · 1003 participants
Moderate

Summary of findings 3: Efficacy and safety of IVT pegcetacoplan 4‐weekly (monthly) vs sham

Loss of ≥ 15 letters BCVA at 1 year · adults with GA due to AMD

The review found no eligible studies for this question.

1 finding from 1 review

Complement inhibitors for age‐related macular degeneration 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings 3: Efficacy and safety of IVT pegcetacoplan 4‐weekly (monthly) vs sham

Change in LLVA from baseline at 1 year (ETDRS letters) · adults with GA due to AMD

1 finding from 1 review

Complement inhibitors for age‐related macular degeneration 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 164 participants
Moderate

Summary of findings 3: Efficacy and safety of IVT pegcetacoplan 4‐weekly (monthly) vs sham

QoL · adults with GA due to AMD

The review found no eligible studies for this question.

1 finding from 1 review

Complement inhibitors for age‐related macular degeneration 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments

Effectiveness of treatment · health problem or population

3 findings from 1 review

Surgical interventions for the management of chronic pelvic pain in women 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 74 participants
Very low
Surgical interventions for the management of chronic pelvic pain in women 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 74 participants
Very low
Surgical interventions for the management of chronic pelvic pain in women 2021 · Cochrane Headline outcomes only
OR 1.26 [0.4, 3.93]
1 study · 51 participants
Low

Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments

Adverse events · health problem or population

1 finding from 1 review

Surgical interventions for the management of chronic pelvic pain in women 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 121 participants
GRADE not reported

Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments

Psychological outcomes ‐ not reported · health problem or population

The review found no eligible studies for this question.

1 finding from 1 review

Surgical interventions for the management of chronic pelvic pain in women 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments

Quality of life ‐ not reported · health problem or population

The review found no eligible studies for this question.

1 finding from 1 review

Surgical interventions for the management of chronic pelvic pain in women 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments

Analgesia requirements · health problem or population

1 finding from 1 review

Surgical interventions for the management of chronic pelvic pain in women 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 74 participants
GRADE not reported

Summary of findings: risk of intermediate hyperglycaemia (IFG5.6 mmol/L definition) vs normoglycaemia

HR: 4 IRR: 6 OR: 10

1 finding from 1 review

Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia 2018 · Cochrane Headline outcomes only
no estimate extracted
2385 participants
Low

Summary of findings: risk of intermediate hyperglycaemia (IFG5.6 mmol/L definition) vs normoglycaemia

HR: 3 IRR: 3 OR: 9

1 finding from 1 review

Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia 2018 · Cochrane Headline outcomes only
no estimate extracted
5685 participants
Low