Number of participants reporting an adverse event · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
Intravenous ketorolac showed no clear difference in number of participants reporting any adverse event compared with placebo (moderate certainty).
1 finding from 1 review
Number of participants experiencing any serious adverse events · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
Intravenous ketorolac showed no clear difference in number of participants experiencing a serious adverse event compared with placebo (low certainty).
1 finding from 1 review
At least 50% reduction in pain · health problem or population
It is very uncertain whether summary of Findings Table ‐ Ibuprofen changes number of participants with at least 50% pain relief at 4 hours compared with placebo (very low certainty).
2 findings from 1 review
Number of participants using rescue medication over 4 to 6 hours postinterventions · health problem or population
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Median (mean) time to use of rescue medication · health problem or population
1 finding from 1 review
Number of participants reporting an adverse event · health problem or population
Summary of Findings Table ‐ Ibuprofen showed no clear difference in number of participants reporting or experiencing any adverse event compared with placebo (low certainty).
1 finding from 1 review
Number of participants experiencing any serious adverse events · health problem or population
1 finding from 1 review
no estimate extracted
1 study · 1 participants
Very low
Diabetes · Adults with mental disorders in low‐ and middle‐income countries
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Drop‐out Objective · Adults with mental disorders in low‐ and middle‐income countries
Melatonin showed no clear difference in drop‐outs (8 weeks) compared with placebo (low certainty).
1 finding from 1 review
Fasting blood glucose (mg/dL) · Adults with mental disorders in low‐ and middle‐income countries
1 finding from 1 review
Fasting blood glucose (8 to 12 weeks) (change from baseline data) · Adults with mental disorders in low‐ and middle‐income countries
1 finding from 1 review
Body‐mass index (BMI) · Adults with mental disorders in low‐ and middle‐income countries
1 finding from 1 review
Diabetes · Adults with mental disorders in low‐ and middle‐income countries
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Drop‐out Objective · Adults with mental disorders in low‐ and middle‐income countries
Metformin showed no clear difference in drop‐outs (12 to 14 weeks) compared with placebo (moderate certainty).
1 finding from 1 review
Fasting blood glucose (mg/dL) · Adults with mental disorders in low‐ and middle‐income countries
2 findings from 1 review
Body‐mass index (BMI) · Adults with mental disorders in low‐ and middle‐income countries
1 finding from 1 review
Incidence of breast hematoma · women undergoing breast surgery
NSAID showed no clear difference in incidence of breast hematoma compared with placebo (low certainty).
1 finding from 1 review
Pain intensity 24 (± 12) hours following surgery · women undergoing breast surgery
1 finding from 1 review
Number of patients with postoperative nausea and vomiting (24 hours postoperatively) · women undergoing breast surgery
NSAID showed no clear difference in incidence rate or severity of postoperative nausea, vomiting, or both compared with placebo (low certainty).
1 finding from 1 review
Bleeding from any location within 90 days · women undergoing breast surgery
NSAID showed no clear difference in bleeding from any location within 90 days compared with placebo (low certainty).
1 finding from 1 review