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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,558 questions in 115 reviews · Vascular

current versions
No studies 346 · 22.2%Ungraded 90 · 5.8%Very low 281 · 18%Low 477 · 30.6%Moderate 313 · 20.1%High 51 · 3.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intervention NR
Proximal DVT · Hospitalised patients1
Graduated compression stockings for prevention of deep vein thrombosis (2018) · Cochrane
OR 0.26 [0.13, 0.53]8 studies · 1035 participantsModerate
Intervention NR
Pulmonary embolism · Hospitalised patients1
Graduated compression stockings for prevention of deep vein thrombosis (2018) · Cochrane
OR 0.38 [0.15, 0.96]5 studies · 569 participantsLow
Intervention NR
Adverse effects and complications · Hospitalised patients1
Graduated compression stockings for prevention of deep vein thrombosis (2018) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Deep vein thrombosis (DVT) · Patients hospitalised for surgical procedures1
Graduated compression stockings for prevention of deep vein thrombosis (2018) · Cochrane
OR 0.35 [0.28, 0.44]19 studies · 2693 participantsHigh
Intervention NR
Proximal DVT · Patients hospitalised for surgical procedures1
Graduated compression stockings for prevention of deep vein thrombosis (2018) · Cochrane
OR 0.26 [0.13, 0.53]7 studies · 875 participantsModerate
Intervention NR
Pulmonary embolism · Patients hospitalised for surgical procedures1
Graduated compression stockings for prevention of deep vein thrombosis (2018) · Cochrane
OR 0.38 [0.15, 0.96]5 studies · 569 participantsLow
Intervention NR
Adverse effects and complications · Patients hospitalised for surgical procedures1
Graduated compression stockings for prevention of deep vein thrombosis (2018) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Deep vein thrombosis (DVT) · Patients hospitalised following acute myocardial infarction
Graduated compression stockings for prevention of deep vein thrombosis (2018) · Cochrane
OR 0.12 [0.03, 0.51]NRLow
Autologous vein vs other graft types
Primary patency (24 months) · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
OR 0.59 [0.37, 0.94]NRLow
Externally supported graft vs unsupported graft
Primary patency (60 months) · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
no estimate extractedNRNo studies
Externally supported graft vs unsupported graft
Secondary patency (24 months) · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
OR 2.25 [1.24, 4.07]NRLow
Externally supported graft vs unsupported graft
Limb salvage · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
no estimate extractedNRNo studies
PTFE vs PTFE with vein cuff
Primary patency (24 months) · people with peripheral vascular disease requiring below‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
OR 1.08 [0.58, 2.01]NRVery low
PTFE vs PTFE with vein cuff
Primary patency (60 months) · people with peripheral vascular disease requiring below‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
no estimate extractedNRNo studies
PTFE vs PTFE with vein cuff
Secondary patency (24 months) · people with peripheral vascular disease requiring below‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
OR 1.22 [0.67, 2.23]NRVery low
PTFE vs PTFE with vein cuff
Limb salvage (24 months) · people with peripheral vascular disease requiring below‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
OR 1.34 [0.72, 2.49]NRLow
Autologous vein vs other graft types
Primary patency (60 months) · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
OR 0.47 [0.28, 0.8]NRModerate
Autologous vein vs other graft types
Secondary patency (60 months) · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
OR 0.41 [0.22, 0.74]NRLow
Autologous vein vs other graft types
Limb salvage · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
no estimate extractedNRNo studies
PTFE vs Dacron
Primary patency (24 months) · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
OR 1.23 [0.92, 1.65]NRLow
PTFE vs Dacron
Primary patency (60 months) · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
OR 1.67 [0.96, 2.9]NRLow
PTFE vs Dacron
Secondary patency (24 months) · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
OR 1.54 [1.04, 2.28]NRLow
PTFE vs Dacron
Limb salvage (24 months) · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
OR 0.82 [0.27, 2.48]NRLow
Externally supported graft vs unsupported graft
Primary patency (24 months) · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
Graft type for femoro‐popliteal bypass surgery (2018) · Cochrane
OR 2.08 [1.29, 3.35]NRLow
Intervention NR
Limb salvage at 30 days · patients seeking treatment for initial management of acute limb ischaemia
Surgery versus thrombolysis for initial management of acute limb ischaemia (2018) · Cochrane
OR 1.02 [0.41, 2.55]4 studies · 636 participantsLow
Intervention NR
Amputation at 30 days · patients seeking treatment for initial management of acute limb ischaemia
Surgery versus thrombolysis for initial management of acute limb ischaemia (2018) · Cochrane
OR 0.97 [0.51, 1.85]3 studies · 616 participantsLow
Intervention NR
Death at 30 days · patients seeking treatment for initial management of acute limb ischaemia
Surgery versus thrombolysis for initial management of acute limb ischaemia (2018) · Cochrane
OR 0.59 [0.31, 1.14]4 studies · 636 participantsModerate
Intervention NR
Vessel patency at 30 days · patients seeking treatment for initial management of acute limb ischaemia
Surgery versus thrombolysis for initial management of acute limb ischaemia (2018) · Cochrane
OR 0.46 [0.08, 2.76]1 study · 20 participantsVery low
Intervention NR
Major haemorrhage at 30 days · patients seeking treatment for initial management of acute limb ischaemia
Surgery versus thrombolysis for initial management of acute limb ischaemia (2018) · Cochrane
OR 3.22 [1.79, 5.78]4 studies · 1070 participantsLow
Intervention NR
Stroke at 30 days · patients seeking treatment for initial management of acute limb ischaemia
Surgery versus thrombolysis for initial management of acute limb ischaemia (2018) · Cochrane
OR 5.33 [0.95, 30.11]5 studies · 1180 participantsLow
Intervention NR
Distal embolisation at 30 days · patients seeking treatment for initial management of acute limb ischaemia
Surgery versus thrombolysis for initial management of acute limb ischaemia (2018) · Cochrane
OR 31.68 [6.23, 161.07]3 studies · 678 participantsVery low
Treatment of DVT at home vs treatment
Recurrence of VTE · people with diagnosed DVT
Home versus in‐patient treatment for deep vein thrombosis (2018) · Cochrane
RR 0.58 [0.39, 0.86]6 studies · 1708 participantsLow
Treatment of DVT at home vs treatment
Venous gangrene · people with diagnosed DVT
Home versus in‐patient treatment for deep vein thrombosis (2018) · Cochrane
no estimate extractedNRNo studies
Treatment of DVT at home vs treatment
Major bleeding · people with diagnosed DVT
Home versus in‐patient treatment for deep vein thrombosis (2018) · Cochrane
RR 0.67 [0.33, 1.36]6 studies · 1708 participantsLow
Treatment of DVT at home vs treatment
Minor bleeding · people with diagnosed DVT
Home versus in‐patient treatment for deep vein thrombosis (2018) · Cochrane
RR 1.29 [0.94, 1.78]6 studies · 1708 participantsLow
Treatment of DVT at home vs treatment
Death f · people with diagnosed DVT
Home versus in‐patient treatment for deep vein thrombosis (2018) · Cochrane
RR 0.69 [0.44, 1.09]6 studies · 1708 participantsLow
Treatment of DVT at home vs treatment
Patient satisfaction/Quality of life · people with diagnosed DVT
Home versus in‐patient treatment for deep vein thrombosis (2018) · Cochrane
no estimate extracted3 studies · 1031 participantsVery low
Treatment of DVT at home vs treatment
Cost‐effectivenessf · people with diagnosed DVT
Home versus in‐patient treatment for deep vein thrombosis (2018) · Cochrane
no estimate extracted4 studies · 834 participantsVery low
Fondaparinux vs placebo
Symptomatic VTE Ventilation‐perfusion scanning, helical computed tomography, pulmonary angiography, autopsy, ultrasonography, or venography · people with ST of the leg
Treatment for superficial thrombophlebitis of the leg (2018) · Cochrane
RR 0.15 [0.04, 0.5]1 study · 3002 participantsModerate
Prophylactic LMWH vs placebo
Extension or recurrence (or both) of ST · people with ST of the leg
Treatment for superficial thrombophlebitis of the leg (2018) · Cochrane
RR 0.44 [0.26, 0.74]1 study · 222 participantsLow
Prophylactic LMWH vs placebo
Mortality · people with ST of the leg
Treatment for superficial thrombophlebitis of the leg (2018) · Cochrane
no estimate extractedNRNo studies
Prophylactic LMWH vs placebo
Minor bleeding · people with ST of the leg
Treatment for superficial thrombophlebitis of the leg (2018) · Cochrane
no estimate extractedNRNo studies
Prophylactic LMWH vs placebo
Adverse effects of treatment · people with ST of the leg
Treatment for superficial thrombophlebitis of the leg (2018) · Cochrane
no estimate extractedNRNo studies
Therapeutic LMWH vs placebo
Symptomatic VTE · people with ST of the leg
Treatment for superficial thrombophlebitis of the leg (2018) · Cochrane
RR 0.85 [0.23, 3.06]1 study · 218 participantsLow
Therapeutic LMWH vs placebo
Major bleeding · people with ST of the leg
Treatment for superficial thrombophlebitis of the leg (2018) · Cochrane
no estimate extracted1 study · 218 participantsLow
Therapeutic LMWH vs placebo
Extension or recurrence (or both) of ST · people with ST of the leg
Treatment for superficial thrombophlebitis of the leg (2018) · Cochrane
RR 0.46 [0.27, 0.77]1 study · 218 participantsLow
Therapeutic LMWH vs placebo
Mortality · people with ST of the leg
Treatment for superficial thrombophlebitis of the leg (2018) · Cochrane
no estimate extractedNRNo studies
Therapeutic LMWH vs placebo
Minor bleeding · people with ST of the leg
Treatment for superficial thrombophlebitis of the leg (2018) · Cochrane
no estimate extractedNRNo studies
Therapeutic LMWH vs placebo
Adverse effects of treatment · people with ST of the leg
Treatment for superficial thrombophlebitis of the leg (2018) · Cochrane
no estimate extractedNRNo studies
Fondaparinux vs placebo
Major bleeding · people with ST of the leg
Treatment for superficial thrombophlebitis of the leg (2018) · Cochrane
RR 0.99 [0.06, 15.86]1 study · 2987 participantsModerate