Cochrane · systematic review · CD001487

Graft type for femoro‐popliteal bypass surgery

Ambler, GK, Twine, CP · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

VascularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
16
current version
GRADE rated
12
No studies
4
Included studies
NR
No studies 4 · 25%Ungraded 0 · 0%Very low 2 · 12.5%Low 9 · 56.3%Moderate 1 · 6.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Autologous vein compared to other graft types for above‐knee femoro‐popliteal bypass surgery

Population: people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
4 questions
OutcomeEffectEvidenceStatus / GRADE
Primary patency (24 months)
Autologous vein vs other graft types
OR 0.59 [0.37, 0.94]NRLow
Downgraded: risk of bias, imprecision
Primary patency (60 months)
Autologous vein vs other graft types
OR 0.47 [0.28, 0.8]NRModerate
Downgraded: risk of bias, imprecision
Secondary patency (60 months)
Autologous vein vs other graft types
OR 0.41 [0.22, 0.74]NRLow
Downgraded: risk of bias, imprecision
Limb salvage
Autologous vein vs other graft types
no estimate extractedNRNo studies

PTFE compared to Dacron for above‐knee femoro‐popliteal bypass surgery

Population: people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
4 questions
OutcomeEffectEvidenceStatus / GRADE
Primary patency (24 months)
PTFE vs Dacron
OR 1.23 [0.92, 1.65]NRLow
Downgraded: risk of bias, imprecision
Primary patency (60 months)
PTFE vs Dacron
OR 1.67 [0.96, 2.9]NRLow
Downgraded: risk of bias, imprecision
Secondary patency (24 months)
PTFE vs Dacron
OR 1.54 [1.04, 2.28]NRLow
Downgraded: risk of bias, imprecision
Limb salvage (24 months)
PTFE vs Dacron
OR 0.82 [0.27, 2.48]NRLow
Downgraded: risk of bias, imprecision

Externally supported graft compared to unsupported graft for above‐knee femoro‐popliteal bypass surgery

Population: people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
4 questions
OutcomeEffectEvidenceStatus / GRADE
Primary patency (24 months)
Externally supported graft vs unsupported graft
OR 2.08 [1.29, 3.35]NRLow
Downgraded: risk of bias, imprecision
Primary patency (60 months)
Externally supported graft vs unsupported graft
no estimate extractedNRNo studies
Secondary patency (24 months)
Externally supported graft vs unsupported graft
OR 2.25 [1.24, 4.07]NRLow
Downgraded: risk of bias, imprecision
Limb salvage
Externally supported graft vs unsupported graft
no estimate extractedNRNo studies

PTFE compared to PTFE with vein cuff for below‐knee femoro‐popliteal bypass surgery

Population: people with peripheral vascular disease requiring below‐knee femoro‐popliteal bypass surgery
4 questions
OutcomeEffectEvidenceStatus / GRADE
Primary patency (24 months)
PTFE vs PTFE with vein cuff
OR 1.08 [0.58, 2.01]NRVery low
Downgraded: risk of bias, imprecision, inconsistency
Primary patency (60 months)
PTFE vs PTFE with vein cuff
no estimate extractedNRNo studies
Secondary patency (24 months)
PTFE vs PTFE with vein cuff
OR 1.22 [0.67, 2.23]NRVery low
Downgraded: risk of bias, imprecision, inconsistency
Limb salvage (24 months)
PTFE vs PTFE with vein cuff
OR 1.34 [0.72, 2.49]NRLow
Downgraded: risk of bias, imprecision