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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,105 questions in 84 reviews · Metabolic and Endocrine Disorders

current versions
No studies 434 · 39.3%Ungraded 32 · 2.9%Very low 246 · 22.3%Low 237 · 21.4%Moderate 132 · 11.9%High 24 · 2.2%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intervention NR
Health‐related quality of life ( · patients with diabetes mellitus
Cinnamon for diabetes mellitus (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events ( · patients with diabetes mellitus
Cinnamon for diabetes mellitus (2012) · Cochrane
no estimate extracted4 studies · 264 participantsModerate
Intervention NR
Costs ( · patients with diabetes mellitus
Cinnamon for diabetes mellitus (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
HbA1c ( · patients with diabetes mellitus
Cinnamon for diabetes mellitus (2012) · Cochrane
no estimate extracted6 studies · 405 participantsModerate
Interactive computer intervention vs usual care
Health‐related quality of life · adults with overweight or obesity
Interactive computer‐based interventions for weight loss or weight maintenance in overweight or obese people (2012) · Cochrane
no estimate extractedNRNo studies
Interactive computer intervention vs in‐person interventions
Weight regain (change in kg weight) · adults with overweight or obesity
Interactive computer‐based interventions for weight loss or weight maintenance in overweight or obese people (2012) · Cochrane
no estimate extracted3 studies · 955 participantsModerate
Interactive computer intervention vs in‐person interventions
Physical‐activity related outcomes · adults with overweight or obesity
Interactive computer‐based interventions for weight loss or weight maintenance in overweight or obese people (2012) · Cochrane
no estimate extractedNRNo studies
Interactive computer intervention vs in‐person interventions
Cost‐effectiveness · adults with overweight or obesity
Interactive computer‐based interventions for weight loss or weight maintenance in overweight or obese people (2012) · Cochrane
no estimate extracted1 study · 62 participantsUngraded
Interactive computer intervention vs usual care
Adverse effects · adults with overweight or obesity
Interactive computer‐based interventions for weight loss or weight maintenance in overweight or obese people (2012) · Cochrane
no estimate extractedNRNo studies
Interactive computer intervention vs usual care
Weight loss (change in kg weight) · adults with overweight or obesity
Interactive computer‐based interventions for weight loss or weight maintenance in overweight or obese people (2012) · Cochrane
no estimate extracted2 studies · 511 participantsModerate
Interactive computer intervention vs usual care
Weight regain (change in kg weight) · adults with overweight or obesity
Interactive computer‐based interventions for weight loss or weight maintenance in overweight or obese people (2012) · Cochrane
no estimate extracted3 studies · 1004 participantsModerate
Interactive computer intervention vs usual care
Physical‐activity related outcomes · adults with overweight or obesity
Interactive computer‐based interventions for weight loss or weight maintenance in overweight or obese people (2012) · Cochrane
no estimate extractedNRNo studies
Interactive computer intervention vs usual care
Cost‐effectiveness · adults with overweight or obesity
Interactive computer‐based interventions for weight loss or weight maintenance in overweight or obese people (2012) · Cochrane
no estimate extractedNRNo studies
Interactive computer intervention vs in‐person interventions
Health‐related quality of life · adults with overweight or obesity
Interactive computer‐based interventions for weight loss or weight maintenance in overweight or obese people (2012) · Cochrane
no estimate extractedNRNo studies
Interactive computer intervention vs in‐person interventions
Adverse effects · adults with overweight or obesity
Interactive computer‐based interventions for weight loss or weight maintenance in overweight or obese people (2012) · Cochrane
no estimate extractedNRNo studies
Interactive computer intervention vs in‐person interventions
Weight loss (change in kg weight) · adults with overweight or obesity
Interactive computer‐based interventions for weight loss or weight maintenance in overweight or obese people (2012) · Cochrane
no estimate extracted1 study · 319 participantsModerate
Intervention NR
Death from any cause · Patients with type 2 diabetes mellitus
Momordica charantia for type 2 diabetes mellitus (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Morbidity · Patients with type 2 diabetes mellitus
Momordica charantia for type 2 diabetes mellitus (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse effects ( · Patients with type 2 diabetes mellitus
Momordica charantia for type 2 diabetes mellitus (2012) · Cochrane
no estimate extracted4 studies · 479 participantsLow
Intervention NR
Health‐related quality of life · Patients with type 2 diabetes mellitus
Momordica charantia for type 2 diabetes mellitus (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Costs · Patients with type 2 diabetes mellitus
Momordica charantia for type 2 diabetes mellitus (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Change in HbA1c from baseline to endpoint ( · Patients with type 2 diabetes mellitus
Momordica charantia for type 2 diabetes mellitus (2012) · Cochrane
no estimate extracted1 study · 40 participantsVery low
Intervention NR
Diabetic complications · patients with type 1 diabetes mellitus
Continuous glucose monitoring systems for type 1 diabetes mellitus (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Ketoacidosis · patients with type 1 diabetes mellitus
Continuous glucose monitoring systems for type 1 diabetes mellitus (2012) · Cochrane
RR 0.85 [0.32, 2.26]5 studies · 689 participantsLow
Intervention NR
Quality of life ‐ Physical health domain SF‐12 · patients with type 1 diabetes mellitus
Continuous glucose monitoring systems for type 1 diabetes mellitus (2012) · Cochrane
no estimate extracted1 study · 226 participantsVery low
Intervention NR
Quality of life ‐ Mental health domain SF‐12 · patients with type 1 diabetes mellitus
Continuous glucose monitoring systems for type 1 diabetes mellitus (2012) · Cochrane
no estimate extracted1 study · 226 participantsVery low
Intervention NR
Quality of life ‐ Parents SF‐12 · patients with type 1 diabetes mellitus
Continuous glucose monitoring systems for type 1 diabetes mellitus (2012) · Cochrane
no estimate extracted1 study · 226 participantsVery low
Intervention NR
Change in HbA1c (%) · patients with type 1 diabetes mellitus
Continuous glucose monitoring systems for type 1 diabetes mellitus (2012) · Cochrane
no estimate extracted6 studies · 963 participantsModerate
Intervention NR
Severe hypoglycaemia · patients with type 1 diabetes mellitus
Continuous glucose monitoring systems for type 1 diabetes mellitus (2012) · Cochrane
RR 3.26 [0.38, 27.82]1 study · 78 participantsVery low
Intervention NR
Ketoacidosis · patients with type 1 diabetes mellitus
Continuous glucose monitoring systems for type 1 diabetes mellitus (2012) · Cochrane
RR 2.45 [0.1, 58.45]1 study · 78 participantsVery low
Intervention NR
Quality of life ‐ Various features · patients with type 1 diabetes mellitus
Continuous glucose monitoring systems for type 1 diabetes mellitus (2012) · Cochrane
no estimate extracted5 studies · 412 participantsUngraded
Intervention NR
Quality of life ‐ Physical health domain SF‐36 Short form · patients with type 1 diabetes mellitus
Continuous glucose monitoring systems for type 1 diabetes mellitus (2012) · Cochrane
no estimate extracted1 study · 75 participantsVery low
Intervention NR
Quality of life ‐ Mental health domain SF‐36 Short form · patients with type 1 diabetes mellitus
Continuous glucose monitoring systems for type 1 diabetes mellitus (2012) · Cochrane
no estimate extracted1 study · 75 participantsVery low
Intervention NR
Change in HbA1c (%) · patients with type 1 diabetes mellitus
Continuous glucose monitoring systems for type 1 diabetes mellitus (2012) · Cochrane
no estimate extracted2 studies · 562 participantsModerate
Intervention NR
Diabetic complications · patients with type 1 diabetes mellitus
Continuous glucose monitoring systems for type 1 diabetes mellitus (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Severe hypoglycaemia · patients with type 1 diabetes mellitus
Continuous glucose monitoring systems for type 1 diabetes mellitus (2012) · Cochrane
RR 1.05 [0.63, 1.77]5 studies · 689 participantsLow
Intervention NR
Depression remission · adults with diabetes mellitus and depression
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane
OR 2.88 [1.58, 5.25]4 studies · 647 participantsModerate
Intervention NR
Death from any cause · adults with diabetes mellitus and depression
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Health‐related quality of life · adults with diabetes mellitus and depression
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane
no estimate extracted3 studies · 153 participantsLow
Intervention NR
Medication adherence/adverse effects · adults with diabetes mellitus and depression
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane
no estimate extracted1 study · 28 participantsLow
Intervention NR
Metabolic control (HbA1c) [%] · adults with diabetes mellitus and depression
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane
no estimate extracted5 studies · 238 participantsModerate
Intervention NR
Healthcare costs · adults with diabetes mellitus and depression
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Diabetes complications · adults with diabetes mellitus and depression
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Death from any cause · adults with diabetes mellitus and depression
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Health‐related quality of life · adults with diabetes mellitus and depression
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane
no estimate extracted4 studies · 784 participantsLow
Intervention NR
Medication adherence/adverse effects · adults with diabetes mellitus and depression
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane
no estimate extracted1 study · 291 participantsLow
Intervention NR
Glycaemic control (HbA1c) [%] · adults with diabetes mellitus and depression
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane
no estimate extracted4 studies · 441 participantsLow
Intervention NR
Healthcare costs [annual costs and effects] · adults with diabetes mellitus and depression
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane
no estimate extracted1 study · 208 participantsLow
Intervention NR
Depression remission · adults with diabetes mellitus and depression
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane
OR 2.5 [1.21, 5.15]3 studies · 136 participantsLow
Intervention NR
Diabetes complications · adults with diabetes mellitus and depression
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane
no estimate extractedNRNo studies