Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

949 questions · 1,008 findings · 130 reviews · Gynaecology and Fertility

No studies found 195 · 19.3%GRADE not reported 30 · 3%Very low 346 · 34.3%Low 323 · 32%Moderate 101 · 10%High 13 · 1.3%

Intervention not reported

Clinical pregnancy; type of antioxidant (natural conceptions and undergoing fertility treatments) ‐ Melatonin lower dose versus melatonin higher dose№ of participants: 140(2 RCTs) · women with subfertility

The intervention showed no clear difference in clinical pregnancy; type of antioxidant (natural conceptions and… (low certainty).

1 finding from 1 review

Embryo culture supernatant injection vs no intervention

Live birth or ongoing pregnancy · Subfertile women undergoing assisted reproduction

It is very uncertain whether embryo culture supernatant injection changes live birth/ongoing pregnancy compared with no intervention (very low certainty).

1 finding from 1 review

G‐CSF vs no treatment or placebo

Clinical pregnancy rate ‐ unselected or unstated IVF number · Subfertile women undergoing assisted reproduction

G‐CSF showed no clear difference in clinical pregnancy rate ‐ unselected or unstated IVF number compared with no treatment or placebo (low certainty).

1 finding from 1 review