Chlorhexidine oral product (one formulation/concentration) vs Another chlorhexidine formulation, concentration or application frequency
Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Adverse events · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
1 finding from 1 review
Dental fluorosis of aesthetic concern (Dean's Index, TFI, TSIF) · Populations of all ages (mostly children) exposed to drinking water with differing fluoride concentrations
Higher water fluoride concentration (fluoridated water; natural or… may leads to higher dental fluorosis of aesthetic concern (Dean's Index, TFI, TSIF) compared with lower water fluoride concentration (concurrent control) (low certainty).
1 finding from 1 review
Caries development in permanent teeth · People of all ages in a community setting; the included caries studies were all in children aged 3 to 16 years
Initiation of water fluoridation (artificial or natural) may leads to lower caries in permanent teeth (change in DMFT) compared with low/non-fluoridated water (0.4 ppm fluoride or less) (low certainty).
1 finding from 1 review
Adverse effects (loose stools, diarrhoea) · Infants (primary teeth; baseline about 9 to 15 months)
1 finding from 1 review
Adverse effects were not reported in a usable format, but the reported rates of loose stools and diarrhoea were very similar between groups. There were no serious adverse effects during the study. Milgrom 2009.
1 study · 94 participants
GRADE not reported
Change in proportion of caries-free children (deciduous or permanent teeth) · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience)
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events (e.g. ulcers, tooth staining) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
1 finding from 1 review
Chlorhexidine mouthrinse vs Placebo or no intervention (including routine care)
Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
Disparities in caries across socioeconomic status (SES) · People of all ages in a community setting; the included caries studies were all in children aged 3 to 16 years
1 finding from 1 review
There is insufficient information to determine whether initiation of a water fluoridation programme results in a change in disparities in caries levels across SES. Data from 3 observational studies (participants not…
3 studies · 35399 participants
Low
Caries in primary teeth (mean number of decayed primary teeth) · Infants (primary teeth; baseline about 9 to 15 months)
1 finding from 1 review
Change in proportion of caries-free children (permanent teeth) · People of all ages in a community setting; the included caries studies were all in children aged 3 to 16 years
Initiation of water fluoridation (artificial or natural) may leads to higher change in proportion of caries-free children (permanent teeth) compared with low/non-fluoridated water (0.4 ppm fluoride or less) (low certainty).
1 finding from 1 review
Pain, quality of life, patient satisfaction or costs · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
Caries increment in permanent teeth · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
It is very uncertain whether chlorhexidine varnish (10% and 40%) changes caries increment in permanent dentition (DMFS; higher values… compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Early childhood caries experience (mean dmft) · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience)
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects: dental fluorosis · Populations of all ages (mostly children) exposed to drinking water with differing fluoride concentrations
Higher water fluoride concentration (fluoridated water; natural or… may leads to higher dental fluorosis of any level (all severities) compared with lower water fluoride concentration (concurrent control) (low certainty).
1 finding from 1 review
Chlorhexidine spray vs Placebo or no intervention (including routine care)
Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
Chlorhexidine toothpaste vs Placebo or no intervention (including routine care)
Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
Dental caries in permanent teeth · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience)
1 finding from 1 review
Insufficient evidence to determine the effect of the cessation of water fluoridation on caries. One study (Maupome 2001), at high risk of bias, over 3 years found no increase in caries in the fluoride-ended group…
1 study · 9249 participants
Very low
Presence of new caries in the primary teeth · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
It is very uncertain whether chlorhexidine gel (0.12%) changes presence of new caries in the primary teeth compared with no treatment (very low certainty).
1 finding from 1 review
Pain, quality of life, patient satisfaction or costs · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review