Findings

What do systematic reviews say?

2,640 questions · 2,709 findings · 446 reviews

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No studies found 593 · 21.9%GRADE not reported 241 · 8.9%Very low 538 · 19.9%Low 706 · 26.1%Moderate 516 · 19%High 115 · 4.2%

Summary of findings table ‐ Oral classical immunosuppressants (prednisolone or cyclosporine) vs placebo

Long‐term hair regrowth ≥ 75% (greater than 26 weeks of · adults with alopecia areata

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Contact immunotherapy (diphencyprone) + hair growth stimulants (minoxidil) vs contact immunotherapy (diphencyprone)

Long‐term hair regrowth ≥ 75% (greater than 26 weeks of · adults with alopecia areata

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Minoxidil vs placebo

Long‐term hair regrowth ≥ 75% (greater than 26 weeks of · adults with alopecia areata

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Other therapies (cryotherapy) vs other therapies (fractional CO2 laser)

Long‐term hair regrowth ≥ 75% ‐ not reported · adults with alopecia areata

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Oral classical immunosuppressants (betamethasone) vs oral classical immunosuppressants (azathioprine, methotrexate, prednisolone)

Long‐term hair regrowth ≥ 75% (greater than 26 weeks of · adults with alopecia areata

The review found no eligible studies for this question.

1 finding from 1 review

Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life (QoL) We reported this outcome narratively in this review. Here, long‐term results (i.e., at the end of treatment) are presented. In the comparison PAZ versus SUN, QoL was measured using FACIT‐F (score range 0‐52; higher scores rep... · people with a confirmed diagnosis of advanced renal cell carcinoma (combined risk groups) without previous systemic anticancer therapy

The review found no eligible studies for this question.

1 finding from 1 review

First‐line therapy for adults with advanced renal cell carcinoma: a systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Brexpiprazole vs antidepressive agents

Adverse effects: 2. Extrapyramidal ‐ akathisia · participants of any age with a primary diagnosis of major depressive disorder

Brexpiprazole probably leads to higher adverse effects: akathisia (followed up until the end of the longest compared with antidepressive agents (moderate certainty).

1 finding from 1 review

Brexpiprazole versus placebo or other antidepressive agents for treating depression 2023 · Cochrane Headline outcomes only
OR 2.95 [2.06, 4.21]
7 studies · 3358 participants
Moderate

Brexpiprazole vs antidepressive agents

Weight gain · participants of any age with a primary diagnosis of major depressive disorder

Brexpiprazole probably leads to higher adverse effects: weight gain (followed up until the end of the longest compared with antidepressive agents (moderate certainty).

1 finding from 1 review

Brexpiprazole versus placebo or other antidepressive agents for treating depression 2023 · Cochrane Headline outcomes only
OR 3.14 [2.19, 4.49]
9 studies · 3424 participants
Moderate

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Long‐term adverse events · women with breast cancer and one to three positive lymph nodes

1 finding from 1 review

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Exercise prescription plus the use of a wearable fitness tracker vs exercise

Adherence to exercise training (long term) · adults with CF

The review found no eligible studies for this question.

1 finding from 1 review

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Wearable fitness tracker plus text message for personalized feedback and goal setting vs wearable fitness tracker alone

QoL · adults with CF

The review found no eligible studies for this question.

1 finding from 1 review

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Wearable fitness tracker plus text message for personalized feedback and goal setting vs wearable fitness tracker alone

Exercise capacity · adults with CF

The review found no eligible studies for this question.

1 finding from 1 review

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Web‐based application to record, monitor and set goals on physical activity plus usual care vs usual care

Adherence to exercise training (long term) · adolescents and adults with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Web‐based application to record, monitor and set goals on physical activity plus usual care vs usual care

Self‐management behavior (long term) · adolescents and adults with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Web‐based application to record, monitor and set goals on physical activity plus usual care vs usual care

QoL · adolescents and adults with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise prescription plus the use of a wearable fitness tracker vs exercise

Self‐management behavior (long term) · adults with CF

The review found no eligible studies for this question.

1 finding from 1 review

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Web‐based application to record, monitor and set goals on physical activity plus usual care vs usual care

Exercise capacity · adolescents and adults with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Web‐based vs face‐to‐face exercise delivery

Adherence to exercise training (long term) · children and adults with CF

The review found no eligible studies for this question.

1 finding from 1 review

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Web‐based vs face‐to‐face exercise delivery

Self‐management behavior (long term) · children and adults with CF

The review found no eligible studies for this question.

1 finding from 1 review

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Web‐based vs face‐to‐face exercise delivery

QoL · children and adults with CF

The review found no eligible studies for this question.

1 finding from 1 review

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found