Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

426 questions · 433 findings · 18 reviews · Implants and prosthodontics

No studies found 45 · 10.4%GRADE not reported 341 · 78.8%Very low 36 · 8.3%Low 6 · 1.4%Moderate 5 · 1.2%High 0 · 0%

Enzyme cleanser vs Placebo / sham solution

Improvement on denture cleanliness (caregivers' opinion) · Institutionalised elderly wearing maxillary complete dentures (CD)

Enzyme cleanser led to lower improvement on denture cleanliness (caregivers' opinion) compared with placebo / sham solution; GRADE not reported.

1 finding from 1 review
  • Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
    12 weeks
    After 12 weeks using an enzyme denture cleanser ('E'), 8 of 18 caregivers perceived some improvement in CD cleanliness. After using a placebo solution ('Plac'), only 2 of 17 perceived some improvement (Analysis 1.1,…
    1 study · 35 participants
    GRADE not reported

Ultrasound during vertical distraction osteogenesis vs Placebo (no ultrasound) during vertical distraction

Distraction distance (bone gain, mm) · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Ultrasound during vertical distraction osteogenesis showed no clear difference in distraction distance (bone gain, mm) compared with placebo (no ultrasound) during vertical distraction; GRADE not reported.

1 finding from 1 review

Vertical distraction osteogenesis vs Autogenous inlay bone graft (iliac crest)

Vertical bone gain · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical distraction osteogenesis led to higher vertical bone gain compared with autogenous inlay bone graft (iliac crest); GRADE not reported.

1 finding from 1 review

Enzyme cleanser vs Placebo / sham solution

Denture plaque · Institutionalised elderly wearing maxillary complete dentures (CD)
1 finding from 1 review
  • Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
    5 weeks; 3 months
    Both interventions reduced biofilm scores after 2 weeks. However, plaque scores were significantly lower for 'E' after 5 weeks (P < 0.05) and 3 months (P < 0.01), as assessed by Chi2 test. It was not possible to…
    1 study
    GRADE not reported

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer implants (vertical augmentation) vs Short implants (8 to 11 mm) without augmentation

Major complications · Patients with atrophic (resorbed) mandibles needing implants

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… led to higher major complications compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.

1 finding from 1 review

1-stage (non-submerged) implant placement vs 2-stage (submerged) implant placement

Patient preference including aesthetics (split-mouth studies only) · People with dental implants

The review found no eligible studies for this question.

1 finding from 1 review

Inlay autogenous bone graft (iliac crest) vs Autogenous onlay bone graft (iliac crest)

Major complications · Patients with deficient posterior mandibles (4.5 to 10 mm above the mandibular canal) needing implants

Autogenous inlay bone graft (iliac crest) showed no clear difference in major complications compared with autogenous onlay bone graft (iliac crest); GRADE not reported.

1 finding from 1 review

Inlay autogenous bone graft (iliac crest) vs Autogenous onlay bone graft (iliac crest)

Vertical bone gain · Patients with deficient posterior mandibles (4.5 to 10 mm above the mandibular canal) needing implants

Autogenous inlay bone graft (iliac crest) showed no clear difference in vertical bone gain compared with autogenous onlay bone graft (iliac crest); GRADE not reported.

1 finding from 1 review

1-stage (non-submerged) implant placement vs 2-stage (submerged) implant placement

Marginal bone level change · People with dental implants

1-stage (non-submerged) implant placement showed no clear difference in radiographic marginal bone level changes compared with 2-stage (submerged) implant placement; GRADE not reported.

1 finding from 1 review

1-stage (non-submerged) implant placement vs 2-stage (submerged) implant placement

Implant failure · People with dental implants

1-stage (non-submerged) implant placement showed no clear difference in implant failure compared with 2-stage (submerged) implant placement (moderate certainty).

1 finding from 1 review

Brushing vs No treatment (immersion in distilled water)

Microbial counts (total aerobes, anaerobes, yeasts) · Complete denture (CD) wearers in a nursing home
1 finding from 1 review
  • Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
    Moore 1984 found that the seven tested methods were similar and resulted in a significant reduction in total aerobes and anaerobes compared with immersion in distilled water (paired t test, P < 0.05). Some chemical…
    1 study · 12 participants
    GRADE not reported

Vertical distraction osteogenesis vs Autogenous inlay bone graft (iliac crest)

Complications · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical distraction osteogenesis showed no clear difference in complications compared with autogenous inlay bone graft (iliac crest); GRADE not reported.

1 finding from 1 review

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer implants (vertical augmentation) vs Short implants (8 to 11 mm) without augmentation

Implant failure · Patients with atrophic (resorbed) mandibles needing implants

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… showed no clear difference in implant failure compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.

1 finding from 1 review

Vertical distraction osteogenesis vs Autogenous onlay bone graft (mandibular ramus)

Vertical bone gain · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical distraction osteogenesis showed no clear difference in vertical bone gain compared with autogenous onlay bone graft (mandibular ramus); GRADE not reported.

1 finding from 1 review

Any denture cleansing method (mechanical or chemical) vs Another method, sham/placebo, or no treatment

Outcome not reported · Wearers of removable partial dentures (RPD), over the age of 18

The review found no eligible studies for this question.

1 finding from 1 review
  • Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
    No included study assessed removable partial denture (RPD) wearers; all six included trials assessed complete denture wearers (Discussion; Implications for research: 'No included study assessed removable partial…
    0 studies
    No studies found

Vertical distraction osteogenesis vs Autogenous onlay bone graft (mandibular ramus)

Complication at augmentation + donor site · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical distraction osteogenesis showed no clear difference in complication at augmented + donor site compared with autogenous onlay bone graft (mandibular ramus); GRADE not reported.

1 finding from 1 review

Inlay autogenous bone graft (iliac crest) vs Inlay bone substitute (Bio-Oss block)

Prosthesis failure · Patients with atrophic posterior mandibles (5 to 7 mm above the mandibular canal) needing implants

Inlay autogenous bone graft (iliac crest) showed no clear difference in prosthesis failure compared with inlay bone substitute (Bio-Oss block); GRADE not reported.

1 finding from 1 review

1-stage (non-submerged) implant placement vs 2-stage (submerged) implant placement

Complications (biological and biomechanical) · People with dental implants

1-stage (non-submerged) implant placement showed no clear difference in complications (biological and biomechanical) compared with 2-stage (submerged) implant placement; GRADE not reported.

1 finding from 1 review

Autogenous bone block from the chin vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Prosthesis/implant failure (1 year) · Patients with horizontally resorbed maxillary sites needing single implants

Autogenous bone block from the chin showed no clear difference in prosthesis/implant failure (1 year) compared with 100% Bio-Oss + resorbable barrier; GRADE not reported.

1 finding from 1 review

Buccal onlay iliac grafts fixed with titanium screws vs Buccal onlay iliac grafts fixed with resorbable screws (split-mouth)

Implant/prosthesis failure and complications · Patients with resorbed maxillae (incl. atrophic sinuses) needing implants
1 finding from 1 review