Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

442 questions · 468 findings · 55 reviews

No studies found 96 · 20.5%GRADE not reported 54 · 11.5%Very low 172 · 36.8%Low 87 · 18.6%Moderate 40 · 8.5%High 19 · 4.1%

Gamma‐globulin vs control (no preparation or saline preparation)

Rubella cases Initial meta‐analysis ‐ clinical diagnosis or serology +/‐ virus isolation +/‐ clinical signs · susceptible people exposed to rubella

Gamma‐globulin probably leads to lower rubella cases Initial meta‐analysis ‐ clinical diagnosis or serology… compared with control (saline or no treatment) (moderate certainty).

1 finding from 1 review

Gamma‐globulin vs control (no preparation or saline preparation)

Subgroup: rubella cases Estimated dose 0.027 to 0.037 ml/lb11 Clinical diagnosis by 2 physicians · susceptible people exposed to rubella

Gamma‐globulin showed no clear difference in subgroup: rubella cases Estimated dose 0.027 to 0.037 ml/lb11… compared with control (saline or no treatment) (low certainty).

1 finding from 1 review

Gamma‐globulin vs control (no preparation or saline preparation)

Subgroup: rubella cases Estimated dose 0.1 to 0.15 ml/lb11 Serology +/‐ virus isolation +/‐ clinical signs · susceptible people exposed to rubella

Gamma‐globulin leads to lower subgroup: rubella cases Estimated dose 0.1 to 0.15 ml/lb11 Serology… compared with control (saline or no treatment) (high certainty).

1 finding from 1 review

Gamma‐globulin vs control (no preparation or saline preparation)

Subgroup: rubella cases Estimated dose 0.2 to 0.5 ml/lb11 Serology +/‐ virus isolation +/‐ clinical signs · susceptible people exposed to rubella

Gamma‐globulin showed no clear difference in subgroup: rubella cases Estimated dose 0.2 to 0.5 ml/lb11 Serology… compared with control (saline or no treatment) (moderate certainty).

1 finding from 1 review

Summary of findings: whole‐body cryotherapy (WBC) vs control (no WBC or passive rest)

Muscle pain at rest · physically‐active adults partaking in exercise designed to produce delayed onset muscle soreness (most trial participants were male)

It is very uncertain whether summary of findings: whole‐body cryotherapy (WBC) changes muscle soreness: pain at rest (VAS) compared with control (no WBC or passive rest) (very low certainty).

4 findings from 1 review
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Summary of findings: whole‐body cryotherapy (WBC) vs control (no WBC or passive rest)

Adverse events · physically‐active adults partaking in exercise designed to produce delayed onset muscle soreness (most trial participants were male)

The review found no eligible studies for this question.

1 finding from 1 review

Double gloves vs single gloves

Dexterity: outer glove perforations ‐ number of perforations Water leak test or air test · healthcare workers

Double gloves showed no clear difference in dexterity: outer glove perforations ‐ number of perforations Water… compared with single gloves (moderate certainty).

1 finding from 1 review