Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,970 questions · 2,433 findings · 231 reviews

No studies found 303 · 12.5%GRADE not reported 759 · 31.2%Very low 357 · 14.7%Low 476 · 19.6%Moderate 418 · 17.2%High 120 · 4.9%

Inferior oblique disinsertion vs anterior transposition

Proportion of participants with anomalous head position preoperatively with residual head tilt postoperatively · people with unilateral superior oblique palsy

It is very uncertain whether inferior oblique disinsertion changes proportion of participants with anomalous head position… compared with anterior transposition (very low certainty).

1 finding from 1 review

Sugammadex (any dose) vs neostigmine (any dose)

Overall signs of postoperative residual paralysis · Adult patients, ASA I‐IV, who received non‐depolarizing NMBAs

Sugammadex (any dose) probably leads to lower overall signs of postoperative residual paralysis compared with neostigmine (any dose) (moderate certainty).

1 finding from 1 review

Sugammadex 2.0 mg/kg vs neostigmine (any dose)

Risk of adverse events and serious adverse eventsb, bradycardia, PONV, and signs of residual neuromuscular blockade · Adult patients, ASA I‐IV, who received non‐depolarizing NMBAs

The review found no eligible studies for this question.

1 finding from 1 review

Sugammadex 4.0 mg/kg vs neostigmine (any dose)

Risk of adverse events and serious adverse eventsb, bradycardia, PONV, and signs of residual neuromuscular blockade · Adult patients, ASA I‐IV, who received non‐depolarizing NMBAs

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Consistency of dual method use (OCs + condoms) at: 12 months; 24 months · adolescents and women with need for contraception

The intervention probably leads to higher consistency of dual method use (OCs + condoms) at: 12 months; 24… (moderate certainty).

1 finding from 1 review