Pain frequency or change in pain frequency · children (4 to 18 years) with functional abdominal pain disorders
1 finding from 1 review
Withdrawals due to adverse events · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether synbiotic changes withdrawals due to adverse events compared with placebo (very low certainty).
1 finding from 1 review
Serious adverse events · children (4 to 18 years) with functional abdominal pain disorders
1 finding from 1 review
Adverse events (any) · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether synbiotic changes adverse events (any) compared with placebo (very low certainty).
1 finding from 1 review
Pain resolution · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes complete resolution of pain (at study end, as reported by study… compared with placebo (very low certainty).
1 finding from 1 review
Severity of pain (at study end, using the Faces Pain Scale) · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes severity of pain (at study end, using the Faces Pain Scale) compared with placebo (very low certainty).
1 finding from 1 review
Pain frequency or change in pain frequency · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes frequency of pain (at study end, episodes per week) compared with placebo (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes withdrawals due to adverse events compared with placebo (very low certainty).
1 finding from 1 review
Serious adverse events · children (4 to 18 years) with functional abdominal pain disorders
1 finding from 1 review
Adverse events (any) · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes adverse events (any) compared with placebo (very low certainty).
1 finding from 1 review
Treatment success as defined by the authors · children (4 to 18 years) with functional abdominal pain disorders
Synbiotic may leads to higher treatment success (at study end, as reported by study authors) compared with placebo (low certainty).
1 finding from 1 review
Pain resolution · children (4 to 18 years) with functional abdominal pain disorders
Synbiotic showed no clear difference in complete resolution of pain (at study end, as reported by study… compared with placebo (low certainty).
1 finding from 1 review
Limitation of chewing or swallowing · Adults (>18 years) with established dry socket following permanent tooth extraction
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
1 finding from 1 review
No adverse events were reported. Six trials (673 participants) reported no adverse events from the use of chlorhexidine gel; one study (Rubio-Palau 2015) reported gastrointestinal discomfort (30, 18%), dizziness (10,…
7 studies
GRADE not reported
Time to initial pain relief (minutes) · Adults (>18 years) with established dry socket following permanent tooth extraction
Neocone led to higher time to initial pain relief (minutes) compared with alvogyl; GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Tranexamic acid (AMCA cones) showed no clear difference in presence of dry socket compared with placebo (lactose cones); GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Apernyl (acetylsalicylic acid pellet) showed no clear difference in presence of dry socket compared with placebo; GRADE not reported.
1 finding from 1 review
Pain (VAS cm) · Adults (>18 years) with established dry socket following permanent tooth extraction
Advanced platelet rich fibrin (A-PRF) led to lower pain (VAS cm) compared with control (no treatment); GRADE not reported.
1 finding from 1 review
Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
1 finding from 1 review