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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,645 questions in 107 reviews · Wounds
current versionsNo studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Primary closure vs no closure Cosmesis using validated cosmetic outcome score at 4 weeks Scale: Vancouver Scar Scale; lower score = better cosmesis · patients with traumatic wounds due to dog bite Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite (2019) · Cochrane | no estimate extracted | 1 study · 182 participants | Moderate |
Primary closure vs delayed closure Time to complete wound healing · patients with traumatic wounds due to dog bite Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite (2019) · Cochrane | no estimate extracted | NR | No studies |
Primary closure vs delayed closure Proportion of wounds which were infection free on day 7 · patients with traumatic wounds due to dog bite Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite (2019) · Cochrane | RR 0.98 [0.9, 1.07] | 1 study · 120 participants | Very low |
Primary closure vs delayed closure Proportion of wounds which were infection‐free · patients with traumatic wounds due to dog bite Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite (2019) · Cochrane | no estimate extracted | NR | No studies |
Primary closure vs delayed closure Cosmesis using validated cosmetic outcome score at 4 weeks · patients with traumatic wounds due to dog bite Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite (2019) · Cochrane | no estimate extracted | NR | No studies |
Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone Proportion with ulcers healed at 24 months · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | RR 1.17 [1.03, 1.33] | 1 study · 196 participants | Low |
Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure Quality of life · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | no estimate extracted | NR | No studies |
Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure Adverse events2 · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | RR 0.04 [0, 0.6] | 1 study · 39 participants | Very low |
Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure Pain · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | no estimate extracted | NR | No studies |
Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery Proportion of ulcers healed at 12 months · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | RR 0.96 [0.64, 1.43] | 1 study · 22 participants | Very low |
Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery Time to complete healing · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | no estimate extracted | NR | No studies |
Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery Ulcer recurrence at 12 months · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | RR 1.03 [0.15, 6.91] | 1 study · 75 participants | Very low |
Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery Quality of life · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | no estimate extracted | NR | No studies |
Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery Adverse events · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | RR 2.05 [0.86, 4.9] | 1 study · 75 participants | Very low |
Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery Pain · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | no estimate extracted | NR | No studies |
Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone Time to complete healing · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | no estimate extracted | NR | No studies |
Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone Ulcer recurrence at 24 months · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | RR 0.85 [0.26, 2.76] | 2 studies · 208 participants | Very low |
Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone Quality of life · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | no estimate extracted | NR | No studies |
Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone Adverse events · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | no estimate extracted | NR | No studies |
Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone Pain · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | no estimate extracted | NR | No studies |
Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure Proportion of ulcers healed at 24 months · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | RR 0.95 [0.83, 1.09] | 1 study · 39 participants | Very low |
Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure Time to complete healing · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | no estimate extracted | NR | No studies |
Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure Ulcer recurrence at 60 months · participants with venous leg ulcers Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers (2019) · Cochrane | RR 0.47 [0.1, 2.3] | 1 study · 39 participants | Very low |
Bathing of the critically ill with chlorhexidine vs bathing with soap and water or non‐antimicrobial washcloths Hospital‐acquired infections Data collected during ICU stay · people who are critically ill Chlorhexidine bathing of the critically ill for the prevention of hospital‐acquired infection (2019) · Cochrane | no estimate extracted | 8 studies · 21924 participants | Very low |
Bathing of the critically ill with chlorhexidine vs bathing with soap and water or non‐antimicrobial washcloths Mortality Data collected (where reported) in hospital, in the ICU, and at 48 hours · people who are critically ill Chlorhexidine bathing of the critically ill for the prevention of hospital‐acquired infection (2019) · Cochrane | OR 0.87 [0.76, 0.99] | 6 studies · 15798 participants | Very low |
Bathing of the critically ill with chlorhexidine vs bathing with soap and water or non‐antimicrobial washcloths Length of stay in the ICU · people who are critically ill Chlorhexidine bathing of the critically ill for the prevention of hospital‐acquired infection (2019) · Cochrane | no estimate extracted | 6 studies · 18570 participants | Very low |
Bathing of the critically ill with chlorhexidine vs bathing with soap and water or non‐antimicrobial washcloths Adverse effects: skin reactions. Reported as attributable to chlorhexidine or soap and water. Data collected during ICU stay · people who are critically ill Chlorhexidine bathing of the critically ill for the prevention of hospital‐acquired infection (2019) · Cochrane | no estimate extracted | 5 studies · 6365 participants | Very low |
Rigid dressings vs soft dressings Wound healing · people who had undergone transtibial amputations Rigid dressings versus soft dressings for transtibial amputations (2019) · Cochrane | no estimate extracted | 1 study · 56 participants | Very low |
Rigid dressings vs soft dressings Adverse events · people who had undergone transtibial amputations Rigid dressings versus soft dressings for transtibial amputations (2019) · Cochrane | RR 0.65 [0.32, 1.32] | 6 studies · 336 participants | Very low |
Rigid dressings vs soft dressings Physical function ‐ Time from amputation to walking (days) · people who had undergone transtibial amputations Rigid dressings versus soft dressings for transtibial amputations (2019) · Cochrane | no estimate extracted | 1 study · 56 participants | Very low |
Rigid dressings vs soft dressings Length of hospital stay (days) · people who had undergone transtibial amputations Rigid dressings versus soft dressings for transtibial amputations (2019) · Cochrane | no estimate extracted | 1 study · 56 participants | Very low |
Rigid dressings vs soft dressings Patient comfort · people who had undergone transtibial amputations Rigid dressings versus soft dressings for transtibial amputations (2019) · Cochrane | no estimate extracted | NR | No studies |
Rigid dressings vs soft dressings Quality of life · people who had undergone transtibial amputations Rigid dressings versus soft dressings for transtibial amputations (2019) · Cochrane | no estimate extracted | NR | No studies |
Rigid dressings vs soft dressings Cost · people who had undergone transtibial amputations Rigid dressings versus soft dressings for transtibial amputations (2019) · Cochrane | no estimate extracted | NR | No studies |
Fatty acid vs other topical intervention or standard care Pressure ulcer incidence: fatty acid vs olive oil · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | RR 1.28 [0.76, 2.17] | 2 studies · 1060 participants | Low |
Active topical agent vs placebo/control Stage 3 pressure ulcer incidence: Conotrane vs placebo · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | RR 1.25 [0.34, 4.55] | 1 study · 258 participants | Very low |
Active topical agent vs placebo/control Stage 4 pressure ulcer incidence: Conotrane vs placebo · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | RR 0.33 [0.01, 8.11] | 1 study · 258 participants | Very low |
Active topical agent vs placebo/control Adverse events: active lotion vs placebo · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | OR 6.14 [0.29, 129.89] | 1 study · 167 participants | Very low |
Silicone dressing vs no dressing Pressure ulcer incidence · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | RR 0.25 [0.16, 0.41] | 6 studies · 1247 participants | Low |
Silicone dressing vs no dressing Stage 1 pressure ulcer incidence · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | RR 0.27 [0.08, 0.9] | 3 studies · 749 participants | Very low |
Silicone dressing vs no dressing Stage 2 pressure ulcer incidence · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | RR 0.4 [0.17, 0.94] | 4 studies · 1090 participants | Very low |
Silicone dressing vs no dressing Stage 4 pressure ulcer incidence · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | RR 0.2 [0.01, 4.13] | 1 study · 322 participants | Very low |
Silicone dressing vs no dressing Unstageable pressure ulcer incidence · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | RR 0.2 [0.01, 4.09] | 1 study · 366 participants | Very low |
Silicone dressing vs no dressing Deep tissue injury pressure ulcer incidence · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | RR 0.99 [0.06, 15.69] | 1 study · 366 participants | Very low |
Silicone dressing vs no dressing Adverse events · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | no estimate extracted | NR | No studies |
Fatty acid vs other topical intervention or standard care Pressure ulcer incidence: fatty acid vs control compound · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | RR 0.42 [0.22, 0.8] | 1 study · 331 participants | Low |
Other dressing vs control Pressure ulcer incidence: polyurethane film vs hydrocolloid dressing · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | RR 0.58 [0.24, 1.41] | 1 study · 160 participants | Very low |
Other dressing vs control Pressure ulcer incidence: Kang’ huier vs routine care · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | RR 0.42 [0.08, 2.05] | 1 study · 100 participants | Very low |
Other dressing vs control Pressure ulcer incidence: PPD vs no dressing · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | RR 0.18 [0.04, 0.76] | 1 study · 74 participants | Very low |
Other dressing vs control Pressure ulcer incidence: thin polyurethane foam vs no dressing · individuals at risk of pressure ulcer development Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane | RR 1.31 [0.83, 2.07] | 1 study · 74 participants | Low |