Mortality (overall survival) · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
Elective neck dissection (at time of primary tumour resection) probably leads to lower mortality (overall survival) compared with therapeutic (delayed) neck dissection (moderate certainty).
1 finding from 1 review
Disease-free survival · Adults with oral cavity or oropharyngeal cancer
Sentinel node biopsy (neck dissection only if biopsy positive) showed no clear difference in disease-free survival (new disease, progression, and mortality) compared with elective neck dissection (low certainty).
1 finding from 1 review
Locoregional recurrence · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
1 finding from 1 review
Locoregional recurrence: data not presented usably and inconsistent; Pandey 2018 no difference (3/12 vs 3/20); Rastogi 2018 lower recurrence with superselective (Kaplan-Meier P<0.05); 72 participants (2 RCTs).
2 studies · 72 participants
Very low
Disease-free survival · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
Elective neck dissection (at time of primary tumour resection) probably leads to lower disease-free survival (new disease, progression, and mortality) compared with therapeutic (delayed) neck dissection (moderate certainty).
1 finding from 1 review
Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer
1 finding from 1 review
Adverse events: severe acute effects in both groups (subcutaneous fibrosis, telangiectasia, moderate-to-severe oedema, xerostomia, trismus, dysphagia); subcutaneous fibrosis more prevalent with surgery + radiotherapy…
1 study · 35 participants
Very low
Side effects or other adverse events · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
The review found no eligible studies for this question.
1 finding from 1 review
Locoregional recurrence · Adults with oral cavity or oropharyngeal cancer
1 finding from 1 review
Locoregional recurrence: reported difference between groups not statistically significant (P=0.355), but no useable data; 32 participants (1 RCT, Iyer 2015).
1 study · 32 participants
Very low
Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
1 finding from 1 review
Duration of orthodontic treatment: alignment stage (mandibular arch) · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
It is very uncertain whether light-emitting diode (LED) photobiomodulation changes duration of orthodontic treatment: alignment stage (mandibular arch) compared with conventional orthodontic appliance treatment (very low certainty).
1 finding from 1 review
Disease-free survival · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
1 finding from 1 review
Disease-free survival · Adults with oral cavity cancer
It is very uncertain whether elective radical (comprehensive) neck dissection changes disease-free survival (new disease, progression, and mortality) compared with elective selective neck dissection (very low certainty).
1 finding from 1 review
Reported incidence or prevalence of root resorption of the impacted canine and/or incisors and/or first premolars · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
The review found no eligible studies for this question.
1 finding from 1 review
Incidence of eruption of the PDC into the mouth · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
Double primary (canine and first molar) tooth extraction led to higher incidence of eruption of the PDC into the mouth compared with single primary (canine) tooth extraction; GRADE not reported.
4 findings from 1 review
RR 1.28 [1.06, 1.54]
2 studies · 96 participants
GRADE not reported
RR 0.68 [0.35, 1.31]
3 studies · 119 participants
Very low
RR 0.61 [0.29, 1.25]
1 study · 23 participants
GRADE not reported
Show 1 more finding
Effect of severity of PDC displacement towards the midline on the proportion of successful eruptions · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
1 finding from 1 review
Reported improvement in the position of the ectopic canine measured from radiographs · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
The review found no eligible studies for this question.
1 finding from 1 review
Root resorption of adjacent permanent teeth caused by the PDC · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
Extraction of the primary (baby) canine (single primary tooth… showed no clear difference in root resorption of adjacent permanent teeth caused by the PDC compared with no extraction (non-intervention control); GRADE not reported.
1 finding from 1 review
Effect of severity of PDC displacement towards the midline on the proportion of successful eruptions · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
1 finding from 1 review
Table 4 (Naoumova 2015): probability of successful eruption depended on displacement severity; sector 2 (mild) 14/19 (74%) erupted vs sector 4 0/10 erupted; data refer to 59 teeth (mITT).
1 study · 59 participants
GRADE not reported
Incidence of successfully erupted PDC that were favourably positioned · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
Double primary (canine and first molar) tooth extraction showed no clear difference in incidence of successfully erupted PDC that were favourably positioned compared with single primary (canine) tooth extraction; GRADE not reported.
3 findings from 1 review
RR 1.64 [0.33, 8.03]
1 study · 23 participants
GRADE not reported
RR 1.09 [0.08, 15.42]
1 study · 23 participants
GRADE not reported
RR 1.64 [0.33, 8.03]
1 study · 23 participants
GRADE not reported
Any other adverse effects of the interventions, such as gingival disease and demineralisation · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
The review found no eligible studies for this question.
1 finding from 1 review
Time taken for the canine to erupt into the mouth · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found