Findings

What do systematic reviews say?

690 questions · 711 findings · 93 reviews

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No studies found 167 · 23.5%GRADE not reported 36 · 5.1%Very low 181 · 25.5%Low 202 · 28.4%Moderate 100 · 14.1%High 25 · 3.5%

Summary of findings: ACBT vs exercise

Personal preference · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: ACBT vs exercise

Adverse events · adults and children with cystic fibrosis

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 19 participants
Very low

Summary of findings: ACBT vs exercise

FEV1 % predicted: absolute change from baseline · adults and children with cystic fibrosis

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 19 participants
Very low

Summary of findings: ACBT vs exercise

FVC (% predicted) Change from baseline · adults and children with cystic fibrosis

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 19 participants
Very low

Summary of findings: ACBT vs exercise

Sputum weight (change from baseline) · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: ACBT vs exercise

Pulmonary exacerbations · adults and children with cystic fibrosis

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
Very low

Summary of findings: ACBT vs CCPT

FEV1 % predicted: absolute change from baseline · adults and children with cystic fibrosis

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
GRADE not reported

Summary of findings: ACBT vs CCPT

FVC (% predicted) Change from baseline · adults and children with cystic fibrosis

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
GRADE not reported

Summary of findings: ACBT vs CCPT

Sputum weight (change from baseline) · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: ACBT vs CCPT

Pulmonary exacerbations · adults and children with cystic fibrosis

Summary of findings: ACBT showed no clear difference in number of pulmonary exacerbations compared with CCPT (low certainty).

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
RR 1.64 [0.62, 4.34]
1 study · 63 participants
Low

Summary of findings: ACBT vs PEP mask therapy

Quality of life (change from baseline) in SF‐36 score and CRQ score · adults and children with cystic fibrosis

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

Summary of findings: ACBT vs PEP mask therapy

Personal preference · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: Defibrotide vs no treatment

Incidence of hepatic veno‐occlusive disease ( · Children undergoing stem cell transplant with malignant and non‐malignant diseases and risk factors for hepatic veno‐occlusive disease

Summary of findings: Defibrotide showed no clear difference in incidence of hepatic veno‐occlusive disease ( compared with no treatment (low certainty).

1 finding from 1 review

Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem cell… 2015 · Cochrane Headline outcomes only
RR 0.62 [0.38, 1.02]
1 study · 360 participants
Low

Summary of findings: Defibrotide vs no treatment

Overall survival ( · Children undergoing stem cell transplant with malignant and non‐malignant diseases and risk factors for hepatic veno‐occlusive disease

Summary of findings: Defibrotide showed no clear difference in overall survival ( compared with no treatment (low certainty).

1 finding from 1 review

Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem cell… 2015 · Cochrane Headline outcomes only
HR 1.04 [0.54, 2.02]
1 study · 356 participants
Low

Summary of findings: Defibrotide vs no treatment

All‐cause mortality at 100 days post‐transplant · Children undergoing stem cell transplant with malignant and non‐malignant diseases and risk factors for hepatic veno‐occlusive disease

Summary of findings: Defibrotide showed no clear difference in all‐cause mortality at 100 days post‐transplant ( compared with no treatment (low certainty).

1 finding from 1 review

Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem cell… 2015 · Cochrane Headline outcomes only
RR 1.05 [0.56, 1.97]
1 study · 360 participants
Low

Summary of findings: Defibrotide vs no treatment

Mortality attributable to hepatic veno‐occlusive disease ( · Children undergoing stem cell transplant with malignant and non‐malignant diseases and risk factors for hepatic veno‐occlusive disease

Summary of findings: Defibrotide showed no clear difference in mortality attributable to hepatic veno‐occlusive disease ( compared with no treatment (low certainty).

1 finding from 1 review

Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem cell… 2015 · Cochrane Headline outcomes only
RR 0.4 [0.13, 1.24]
1 study · 360 participants
Low

Summary of findings: Defibrotide vs no treatment

Quality of life · Children undergoing stem cell transplant with malignant and non‐malignant diseases and risk factors for hepatic veno‐occlusive disease

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem cell… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: Defibrotide vs no treatment

Frequency of adverse events ( · Children undergoing stem cell transplant with malignant and non‐malignant diseases and risk factors for hepatic veno‐occlusive disease

It is very uncertain whether summary of findings: Defibrotide changes frequency of adverse events ( compared with no treatment (very low certainty).

1 finding from 1 review

Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem cell… 2015 · Cochrane Headline outcomes only
RR 18.79 [1.1, 320.45]
1 study · 360 participants
Very low

Antioxidants vs placebo

Muscle soreness · mainly physically active individuals1 partaking in exercise2 designed to produce delayed onset muscle soreness

Summary of findings: antioxidants showed no clear difference in muscle soreness compared with placebo (low certainty).

5 findings from 1 review

Antioxidants for preventing and reducing muscle soreness after exercise 2017 · Cochrane Headline outcomes only
no estimate extracted
21 studies · 525 participants
Low
Antioxidants for preventing and reducing muscle soreness after exercise 2017 · Cochrane Headline outcomes only
no estimate extracted
41 studies · 936 participants
Moderate
Antioxidants for preventing and reducing muscle soreness after exercise 2017 · Cochrane Headline outcomes only
no estimate extracted
45 studies · 1047 participants
Low

Show 2 more findings

Antioxidants for preventing and reducing muscle soreness after exercise 2017 · Cochrane Headline outcomes only
no estimate extracted
28 studies · 657 participants
Moderate
Antioxidants for preventing and reducing muscle soreness after exercise 2017 · Cochrane Headline outcomes only
no estimate extracted
17 studies · 436 participants
Low

Antioxidants vs placebo

Subjective recovery · mainly physically active individuals1 partaking in exercise2 designed to produce delayed onset muscle soreness

The review found no eligible studies for this question.

1 finding from 1 review

Antioxidants for preventing and reducing muscle soreness after exercise 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found