Findings

What do systematic reviews say?

511 questions · 561 findings · 70 reviews · Gynaecology and Fertility

Sort:Best matchNewest Highest certainty Download CSV

No studies found 91 · 16.2%GRADE not reported 5 · 0.9%Very low 140 · 25%Low 219 · 39%Moderate 98 · 17.5%High 8 · 1.4%

Chinese herbal medicines vs placebo

Vasomotor SymptomsOverall scores of hot flushes in a diary (daily) · women with menopausal symptoms

1 finding from 1 review

Chinese herbal medicine for menopausal symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 263 participants
Low

Chinese herbal medicines vs placebo

Vasomotor SymptomsOverall scores of hot flushes in a diary (monthly) · women with menopausal symptoms

1 finding from 1 review

Chinese herbal medicine for menopausal symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 84 participants
Very low

Chinese herbal medicines vs placebo

Vasomotor symptoms: night sweats · women with menopausal symptoms

2 findings from 1 review

Chinese herbal medicine for menopausal symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 64 participants
Low
Chinese herbal medicine for menopausal symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 84 participants
Very low

Chinese herbal medicines vs placebo

Vasomotor Symptomsmeasured by the Kupperman Index (KI, monthly) · women with menopausal symptoms

1 finding from 1 review

Chinese herbal medicine for menopausal symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 69 participants
Low

Chinese herbal medicines vs placebo

Vasomotor symptoms (vasomotor) · women with menopausal symptoms

1 finding from 1 review

Chinese herbal medicine for menopausal symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 256 participants
Low

Chinese herbal medicines vs placebo

Adverse effects · women with menopausal symptoms

It is very uncertain whether chinese herbal medicine (CHM) changes adverse Effects compared with placebo (very low certainty).

1 finding from 1 review

Chinese herbal medicine for menopausal symptoms 2016 · Cochrane Headline outcomes only
RR 1.51 [0.69, 3.33]
7 studies · 705 participants
Very low

Transdermal beta‐estradiol patch vs placebo

Hot flush frequency (number/day) · women with hot flushes

Transdermal beta‐estradiol patch showed no clear difference in frequency of hot flushes Beta‐estradiol patch 0.0375‐0.10 mg/day compared with placebo (low certainty).

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 793 participants
Low

Intranasal beta‐estradiol vs placebo

Change in frequency of hot flushes from baseline to end of study · women with hot flushes

Intranasal beta‐estradiol showed no clear difference in frequency of hot flushes Change from baseline Intranasal… compared with placebo (moderate certainty).

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 458 participants
Moderate

Intranasal beta‐estradiol vs placebo

Adverse effects Intranasal beta‐estradiol 0.021 mg/day, 0.029 mg/day or 0.040 mg/day · women with hot flushes

Intranasal beta‐estradiol probably leads to higher adverse effects Intranasal beta‐estradiol 0.021 mg/day, 0.029 mg/day… compared with placebo (moderate certainty).

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
OR 1.96 [1.26, 3.03]
1 study · 458 participants
Moderate

Transdermal beta‐estradiol patch vs placebo

Intensity of hot flushes Beta‐estradiol patch 0.025‐0.05 mg/day · women with hot flushes

Transdermal beta‐estradiol patch showed no clear difference in intensity of hot flushes Beta‐estradiol patch 0.025‐0.05 mg/day compared with placebo (low certainty).

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 393 participants
Low

Transdermal beta‐estradiol patch vs placebo

Adverse effects Beta‐estradiol patch dose 0.10 mg/day · women with hot flushes

Transdermal beta‐estradiol patch may leads to higher adverse effects Beta‐estradiol patch dose 0.10 mg/day compared with placebo (low certainty).

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
OR 2.14 [1.29, 3.54]
9 studies · 1822 participants
Low

Transdermal beta‐estradiol gel vs placebo

Hot flush frequency (number/day) · women with hot flushes

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 930 participants
Low

Transdermal beta‐estradiol gel vs placebo

Adverse effects Beta‐estradiol gel dose 1.5 mg/day · women with hot flushes

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1086 participants
Moderate

Oral beta‐estradiol vs placebo

Hot flush frequency (number/day) · women with hot flushes

Oral beta‐estradiol showed no clear difference in frequency of hot flushes Oral beta‐estradiol 0.5‐1.0 mg/day compared with placebo (low certainty).

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 356 participants
Low

Oral beta‐estradiol vs placebo

Adverse effects Oral beta‐estradiol 0.5‐2.0 mg/day · women with hot flushes

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 433 participants
Low

Topical beta‐estradiol emulsion vs placebo

Rate of vasomotor symptoms ‐ · women with vasomotor symptoms

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 200 participants
Low

Topical beta‐estradiol emulsion vs placebo

Adverse effects Micellar nanoparticle beta‐estradiol 8.6 mg/day · women with vasomotor symptoms

Topical beta‐estradiol emulsion showed no clear difference in adverse effects Micellar nanoparticle beta‐estradiol 8.6 mg/day compared with placebo (low certainty).

1 finding from 1 review

Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
OR 1.46 [0.8, 2.66]
1 study · 200 participants
Low

NSAIDs vs placebo

Relief of pain · women with primary dysmenorrhoea

NSAIDs may leads to higher pain relief dichotomous data compared with placebo (low certainty).

1 finding from 1 review

Nonsteroidal anti‐inflammatory drugs for dysmenorrhoea 2015 · Cochrane Headline outcomes only
OR 4.37 [3.76, 5.09]
Studies not reported
Low

NSAIDs vs placebo

All adverse effects · women with primary dysmenorrhoea

NSAIDs may leads to higher all adverse effects compared with placebo (low certainty).

1 finding from 1 review

Nonsteroidal anti‐inflammatory drugs for dysmenorrhoea 2015 · Cochrane Headline outcomes only
OR 1.29 [1.11, 1.51]
Studies not reported
Low

Misoprostol vs placebo or no treatment before operative hysteroscopy

Ease of dilatation: need for mechanical dilatation · Pre and post menopausal women

Misoprostol probably leads to lower ease of dilatation: need for mechanical dilatation compared with placebo or no treatment before operative hysteroscopy (moderate certainty).

1 finding from 1 review

Preoperative ripening of the cervix before operative hysteroscopy 2015 · Cochrane Headline outcomes only
OR 0.08 [0.04, 0.16]
5 studies · 441 participants
Moderate