Cochrane · systematic review · CD009023
Chinese herbal medicine for menopausal symptoms
Zhu, X, Liew, Y, Liu, ZL · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Gynaecology and FertilityAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
11
No studies
1
Included studies
NR
No studies 1 · 8.3%Ungraded 0 · 0%Very low 5 · 41.7%Low 4 · 33.3%Moderate 2 · 16.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Chinese herbal medicine (CHM) compared with placebo for menopausal symptoms
Population: women with menopausal symptoms
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Vasomotor SymptomsFrequency of hot flushes measured in a diary (daily) Chinese herbal medicine (CHM) vs placebo | no estimate extracted | 2 studies · 199 participants | Moderate Downgraded: imprecision |
Vasomotor SymptomsSeverity of hot flushes measured in a diary (daily) Chinese herbal medicine (CHM) vs placebo | no estimate extracted | 1 study · 108 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Vasomotor SymptomsOverall scores of hot flushes in a diary (daily) Chinese herbal medicine (CHM) vs placebo | no estimate extracted | 3 studies · 263 participants | Low Downgraded: imprecision |
Vasomotor SymptomsOverall scores of hot flushes in a diary (monthly) Chinese herbal medicine (CHM) vs placebo | no estimate extracted | 1 study · 84 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Vasomotor SymptomsOverall night sweats in a diary (daily) Chinese herbal medicine (CHM) vs placebo | no estimate extracted | 1 study · 64 participants | Low Downgraded: imprecision |
Vasomotor SymptomsOverall scores of night sweats in a diary (monthly) Chinese herbal medicine (CHM) vs placebo | no estimate extracted | 1 study · 84 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Vasomotor Symptomsmeasured by the Kupperman Index (KI, monthly) Chinese herbal medicine (CHM) vs placebo | no estimate extracted | 1 study · 69 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Vasomotor Symptomsmeasured by Menopause Specific Quality of Life Questionnaire (MENQOL, monthly) Chinese herbal medicine (CHM) vs placebo | no estimate extracted | 3 studies · 256 participants | Low Downgraded: imprecision |
Adverse Effects Chinese herbal medicine (CHM) vs placebo | RR 1.51 [0.69, 3.33] | 7 studies · 705 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
CHM compared with HT for menopausal symptoms
Population: Women with menopausal symptoms
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Outcomesa CHM vs HT | no estimate extracted | NR | No studies |
Vasomotor Symptoms measured by Menopause Specific Quality of Life Questionnaire (MENQOL, monthly) CHM vs HT | no estimate extracted | 2 studies · 127 participants | Very low Downgraded: risk of bias, imprecision |
Adverse Effects CHM vs HT | RR 0.96 [0.66, 1.39] | 6 studies · 864 participants | Very low Downgraded: risk of bias, imprecision |